ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Aclasta

Name: Aclasta 5mg/100ml IV Infusion
Brand: Novartis (Bangladesh) Ltd.
SKU: 24749
Price: 35423.59 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

IV Infusion - (5mg/100ml)

Novartis (Bangladesh) Ltd.

Generic: Zoledronic Acid 5mg

Safety Advices

বাংলা

English

CAUTION

Caution is advised when consuming alcohol with Aclasta. Please consult your doctor.

CONSULT YOUR DOCTOR

Aclasta is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

CONSULT YOUR DOCTOR

Aclasta is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

UNSAFE

Aclasta may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

CONSULT YOUR DOCTOR

There is limited information available on the use of Aclasta in patients with kidney disease. Please consult your doctor.

CONSULT YOUR DOCTOR

There is limited information available on the use of Aclasta in patients with liver disease. Please consult your doctor.

Medicine Overview of Aclasta 5mg/100ml IV Infusion

Introduction

Aclasta is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids. Using this medicine can reduce your risk of breaking bones. It is also used to treat high levels of calcium in people who have cancer. Aclasta is given by a doctor or nurse. How much you are given, and how often, will be decided by your doctor. It may just be a single injection or you may need regular injections depending upon your underlying condition. Your doctor will ask you to drink plenty of water before the injection, to avoid getting...

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Uses of Aclasta

Osteoporosis
Hypercalcemia

Side effects of Aclasta

Common

Headache
Back pain
Musculoskeletal (bone, muscle or joint) pain
Heartburn
Diarrhea

How to use Aclasta

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Aclasta works

Aclasta is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

What if you forget to take Aclasta?

If you miss a dose of Aclasta. Please consult your doctor.

Quick Tips

You have been prescribed Rokfos Solution for infusion for the treatment of osteoporosis.

It may also be used to treat high blood calcium levels (hypercalcemia) or bone damage and pain that may occur with cancer.

It is given by injection into a vein, usually over at least 15 minutes or as directed by your doctor.

Drink plenty of fluids to prevent dehydration and kidney damage.

It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor.

You may develop fever or flu like symptoms, such as chills, tiredness and weakness. These are usually temporary and should go away after a few days. You may take a pain reliever/fever reducer to prevent or treat these symptoms.

Rokfos Solution for infusion may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in your jaw.

Your doctor will monitor your response to Rokfos Solution for infusion by testing your bone mineral density (BMD). This is usually done every 1-3 years.

Do not take Rokfos Solution for infusion if you are pregnant or breastfeeding.

Brief Description

Indication

Paget's disease of bone, Postmenopausal osteoporosis, Corticosteroid-induced osteoporosis

Administration

Reconstitute powder with 5 mL SWI; once powder is fully dissolved, dilute further in 100 mL NS or D5W before administering

Adult Dose

Paget's disease of bone Adult: 5 mg as a single infusion over 15 min. Patients should receive elemental Ca 1,500 mg and vit D 800 IU daily particularly w/in 2 wk after admin. Patients who have relapsed: May be given an additional infusion of 5 mg after an interval of at least 1 yr from the initial dose. Osteoporosis in postmenopausal women; Increase bone mass in men with osteoporosis; Corticosteroid-induced osteoporosis Adult: 5 mg as a single infusion over at least 15 min, once yrly, w/ adequate Ca and vit D intake. Patients w/ low-trauma hip fracture: Start 2 or...

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Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment CrCl >35 mL/min: No adjustment needed CrCl <35 mL/min: Contraindicated

Contraindication

The drug is contraindicated if patients have hypersensitivity to the active substance or to any of the excipients or to any bisphosphonates, hypocalcaemia, renal impairment (creatinine clearance <35 mL/min), current or recent uveitis, or a history of bisphosphonate-associated uveitis, pregnancy and lactation.

Mode of Action

Zoledronic acid, an aminobiphosphonate, is a potent inhibitor of bone resorption. It inhibits osteoclastic activity and skeletal calcium release caused by tumours.

Precaution

Patient w/ aspirin-sensitive asthma. Mild to moderate renal impairment. Pregnancy. Patient Counselling This drug may cause dizziness, if affected, do not drive or operate machinery. Adequately hydrate patients prior to admin. Ensure adequate Ca and vit D intake. Monitoring Parameters Monitor serum Ca, Mg, phosphate and electrolytes; haematocrit/Hb (oncology use); biochemical markers of bone turnover (non-oncology use). Prior to therapy, perform dental exam and preventive dentistry in patients at risk of osteonecrosis. Lactation: Unknown whether drug crosses into breast milk; avoid using

Side Effect

Arthralgia, fever, flu-like symptoms, myalgia, headache, pain in extremity, nausea, vomiting, diarrhoea, eye inflammation; alopecia, hyperhidrosis, bone/joint/muscle pain, osteonecrosis of the jaw, femoral fracture, hypersensitivity reactions (e.g. urticaria, angioedema), Stevens-Johnson syndrome, toxic epidermal necrolysis, hypotension. Potentially Fatal: Severe hypocalcaemia, severe kidney problems.

Interaction

Increased risk of hypocalcaemia with aminoglycosides and loop diuretics. Increased risk renal dysfunction with nephrotoxic agents.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Aclasta

IV Infusion - (5mg/100ml)

Novartis (Bangladesh) Ltd.

Generic: Zoledronic Acid 5mg

Additional Offers

Cashback

৳100

For purchasing above ৳5000+

Cashback

৳80

For purchasing above ৳4000+

Cashback

৳60

For purchasing above ৳3000+

Cashback

৳40

For purchasing above ৳2000+

Cashback

৳20

For purchasing above ৳1000+

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Aclasta

Medicine Overview of Aclasta 5mg/100ml IV Infusion

Aclasta

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