Consuming alcohol with Pemetrex does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Pemetrex is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CAUTION
Pemetrex should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
UNSAFE
Pemetrex may cause side effects which could affect your ability to drive.
Pemetrex may make you feel tired and this may affect your ability to drive.
CAUTION
Pemetrex should be used with caution in patients with kidney disease. Dose adjustment of Pemetrex may be needed. Please consult your doctor.
Use of Pemetrex is not recommended in patients with moderate to severe kidney disease.
SAFE IF PRESCRIBED
Pemetrex is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pemetrex may not be needed in these patients. Please consult your doctor.
Medicine Overview of Pemetrex 500mg/5ml Injection
Introduction
Pemetrex is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.
Pemetrex is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take ...
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Uses of Pemetrex
Non-small cell lung cancer
Malignant pleural mesothelioma
Side effects of Pemetrex
Common
Nausea
Vomiting
Sore throat
Loss of appetite
Stomatitis (Inflammation of the mouth)
Hair loss
Low blood platelets
Rash
Fatigue
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Neuropathy
How to use Pemetrex
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pemetrex works
Pemetrex interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
Quick Tips
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
IV Preparation
Aseptically reconstitute with 20 mL of 0.9% NaCl (preservative free) to give a 25 mg/mL solution
Gently swirl until completely dissol...
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Adult Dose
Intravenous
Malignant Pleural Mesothelioma
Indicated for mesothelioma in combination with cisplatin in patients whose disease is unresectable or are...
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Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
<45 Usage is not recommended.
Contraindication
Hypersensitivity.
Mode of Action
Pemetrexed is a thymidylate synthase inhibitor. It works by inhibiting thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formy...
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Precaution
Monitor CBC, platelet counts, and CrCl for nadir and recovery before each cycle. Periodic hepatic monitoring Premedication with folate and vitamin B12...
High doses of NSAIDs and aspirin may reduce the elimination of pemetrexed; avoid usage 2 days (5 days for longer-acting NSAIDs) before, during and 2 d...
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ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.