It is unsafe to consume alcohol with Pac.

Pac may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Pac should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Pac may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Pac should be used with caution in patients with severe kidney disease. Dose adjustment of Pac may be needed. Please consult your doctor. However, Pac contains paracetamol which is considered the safest painkiller for kidney disease patients.

Pac should be used with caution in patients with liver disease. Dose adjustment of Pac may be needed. Please consult your doctor. However, the use of Pac is not recommended in patients with severe liver disease and active liver disease.