Consuming alcohol with Tygacil does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Tygacil is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Tygacil is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Tygacil may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Tygacil is safe to use in patients with kidney disease. No dose adjustment of Tygacil is recommended.
CAUTION
Tygacil should be used with caution in patients with severe liver disease. Dose adjustment of Tygacil may be needed. Please consult your doctor.
Medicine Overview of Tygacil 50mg/Vial Injection
Introduction
Tygacil is an antibiotic that fights bacteria. It is used to treat severe infections of the body like skin, intra-abdominal infections, and community-acquired bacterial pneumonia. It works by killing the bacteria that cause these problems. But, it will not treat a viral infection. Tygacil is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip or by direct injection into a vein, under the supervision of a healthcare professional. The dose depends on what type of infection you have, where it is in the body and how serious it is. You should have...
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Uses of Tygacil
Severe bacterial infections
Side effects of Tygacil
Common
Headache
Vomiting
Nausea
Increased liver enzymes
Stomach pain
Diarrhea
How to use Tygacil
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Tygacil works
Tygacil is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.
Quick Tips
Tygacil is an antibiotic that is usually only given in the hospital for serious infections.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Tygacil affects you.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
IV Preparation
Reconstitute each vial with 5.3 mL NS or D5W to achieve a conc of 10 mg/mL
IV Administration
Infuse over 30-60 min
Adult Dose
The recommended daily dose is as follows: Adults: The recommended dosage regimen for Tigecycline is an initial dose of 100 mg, followed by 50 mg every 12 hours. Intravenous (IV) infusions of Tigecycline should be administered over approximately 30 to 60 minutes every 12 hours. The duration of therapy should be guided by the severity and site of the infection and the patient's clinical and bacteriological progress. The recommended duration of treatment with Tigecycline for complicated skin and skin structure infections or for complicated intra-abdominal infections is 5 to 14 days and for Community-acquired pneumonia is 7-14 days. Hepatic impairment:...
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Child Dose
<18 years: Safety and efficacy not established
Renal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Hypersensitivity. Hospital-acquired pneumonia and ventilator-associated pneumonia. Use during tooth development.
Mode of Action
Tigecycline is a glycylcycline antibiotic which prevents protein synthesis of the susceptible bacteria by binding to its 30s ribosomal subunit. It is generally considered as bacteriostatic agent; w/ bactericidal activity against S. pneumonia and L. pneumophilia. Tigecycline antibacterial activity covers facultative gm+ve (including MRSA, vancomycin-susceptible Enterococcus faecalis) and gm-ve bacteria, and anaerobic bacteria.
Precaution
Hypersensitivity to tetracyclines. Use tigecycline in situations when alternative treatments are not suitable. Patients w/ complicated intra-abdominal infections secondary to clinically apparent intestinal perforation. Hepatic impairment. Pregnancy and lactation.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.