Zithrin 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Zithrin 500 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
There may be a possibility of diarrhea or rash in the baby.
SAFE
Zithrin 500 does not usually affect your ability to drive.
CAUTION
Zithrin 500 should be used with caution in patients with severe kidney disease. Dose adjustment of Zithrin 500 may be needed. Please consult your doctor.
CAUTION
Zithrin 500 should be used with caution in patients with liver disease. Dose adjustment of Zithrin 500 may be needed. Please consult your doctor.
Medicine Overview of Zithrin 500mg Tablet
Introduction
Zithrin 500 is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases li...
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Uses of Zithrin 500
Bacterial infections
Side effects of Zithrin 500
Common
Vomiting
Nausea
Abdominal pain
Diarrhea
How to use Zithrin 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zithrin 500 may be taken with or without food, but it is better to take it at a fixed time.
How Zithrin 500 works
Zithrin 500 is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading.
What if you forget to take Zithrin 500?
If you miss a dose of Zithrin 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back...
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Take it 1 hour before or two hours after food.
Do not take antacids 2 hours before or after taking Zithrin 500.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood...
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Stop taking Zithrin 500 and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing...
Oral Administration
Tablet: Take tablets without regard to food; however, food may enhance tolerability
Oral suspension
Conventional oral suspens...
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Adult Dose
Adult: PO Resp tract infections; Skin and soft tissue infections
500 mg once daily for 3 days.
Chancroid; Non-gonococcal cervicitis/urethritis due...
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Child Dose
Child: PO: q24h
Otitis: 10 mg/kg/day for 1 day, then 5 mg/kg for 4 days; or 10 mg/kg/day for 3 days; or 30 mg/kg once.
Pharyngitis: 12 mg/kg/day fo...
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Renal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic. Coadministration w/ pimozide. History of cholestatic jaund...
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Mode of Action
Azithromycin is a semisynthetic azalide antibiotic. It blocks transpeptidation by binding to 50s ribosomal subunit of susceptible organisms and disrup...
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Precaution
May increase the risk of Torsades de pointes and fatal heart arrhythmias in patients w/ prolonged QT interval, low K or Mg blood levels, slow heart ra...
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Side Effect
>10%
High single dose therapy
Diarrhea (52.8%),Nausea (32.6%),Abdominal pain (27%),Loose stool (19.1%)
1-10%
Cramping (2-10%),Vaginitis (2-10%),...
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Pregnancy Category Note
Pregnancy
Available data from published literature and postmarketing experience over several decades with azithromycin use in pregnant women have not...
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Interaction
Increases serum concentrations of digoxin, ciclosporin, terfenadine, hexobarbital and phenytoin. Decreased rate of absorption w/ antacids containing a...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.