Flumetasone pivalate is a moderately potent glucocorticoid, usually used for local application. It has an anti-inflammatory, anti-allergic, vasoconstrictive and anti-proliferative effect. Clioquinol, is a bacteriostatic agent that is active against a broad spectrum of pathogenic micro-organisms, including fungi and gram-positive bacteria (e.g. staphylococci). It has only a moderate inhibitory effect on gram-negative bacteria.