Medicine Overview of Actrapid Flexpen 100IU/ml Injection
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Indication
Diabetic ketoacidosis, Diabetes mellitus
Administration
Administer within 15 minutes before a meal or immediately after a meal.
Administer subcutaneously in the upper arm, thigh or abdominal wall. A subcutaneous injection into the abdominal wall results in a faster absorption than from other injection s...
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Adult Dose
Subcutaneous
Type 1 Diabetes Mellitus
Initial: 0.2-0.4 units/kg/day SC divided q8hr or more frequently
Maintenance: 0.5-1 unit/kg/day SC divided q8hr or more frequently; in insulin-resistant patients (eg, due to obesity), substantially higher dai...
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Child Dose
Subcutaneous
Type 1 Diabetes Mellitus
Initial: 0.2-0.4 unit/kg/day SC divided q8hr or more frequently
Maintenance: 0.5-1 unit/kg/day SC divided q8hr or more frequently; in insulin-resistant patients (eg, due to obesity), substantially higher da...
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Renal Dose
Renal impairment: Dose adjustments may be needed.
Contraindication
Hypoglycaemia.Hypersensitivity to any of the components.
Mode of Action
Insulin lowers blood glucose levels. It regulates carbohydrate, protein and fat metabolism by inhibiting hepatic glucose production and lipolysis, and enhancing peripheral glucose disposal. The various insulin formulations are classified according to...
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Precaution
Pregnancy (insulin requirements tend to fall during the 1st trimester, increase during the 2nd and 3rd) and lactation. Caution with decreased insulin requirements: Diarrhea, nausea/vomiting, malabsorption, hypothyroidism, renal impairment, hepatic im...
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