Coadministration with alcohol increases the risk of severe hypotension and syncope (also see Contraindications and Black Box Warnings) Coadministration with moderate or strong CYP3A4 inhibitors is significantly increases flibanserin concentrations, which can lead to hypotension and syncope (also see Contraindications, Black Box Warnings, and Dosing) Concomitant use of multiple weak CYP3A4 inhibitors that may include herbal supplements (eg, ginkgo, resveratrol) or nonprescription drugs (eg, cimetidine) could also lead to clinically relevant increases in flibanserin concentrations that may increase the risk of hypotension and syncope Causes CNS depression (eg, somnolence, sedation); risk of CNS depression is increased if taken during waking...
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