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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Pulbo 801

Name: Pulbo 801mg Tablet
Brand: Opsonin Pharma Limited
SKU: 37998
Price: 1125 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Tablet - (801mg)

Opsonin Pharma Limited

Generic: Pirfenidone

Safety Advices

বাংলা

English

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pulbo 801. Please consult your doctor.

CONSULT YOUR DOCTOR

Pulbo 801 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

CONSULT YOUR DOCTOR

Information regarding the use of Pulbo 801 during breastfeeding is not available. Please consult your doctor.

UNSAFE

Pulbo 801 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

CAUTION

Pulbo 801 should be used with caution in patients with kidney disease. Dose adjustment of Pulbo 801 may be needed. Please consult your doctor. Use of Pulbo 801 is not recommended with severe kidney disease and dialysis patients.

CAUTION

Pulbo 801 should be used with caution in patients with liver disease. Dose adjustment of Pulbo 801 may be needed. Please consult your doctor. Use of Pulbo 801 is not recommended in patients with severe liver disease.

Medicine Overview of Pulbo 801mg Tablet

Introduction

Pulbo 801 is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better. It may be taken with food. But, It is better to take it at the same time every day to get the most benefits. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this...

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Uses of Pulbo 801

Idiopathic pulmonary fibrosis

Side effects of Pulbo 801

Common

Insomnia (difficulty in sleeping)
Headache
Dizziness
Tiredness
Sinus inflammation
Loss of appetite
Upper respiratory tract infection
Weight loss

How to use Pulbo 801

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pulbo 801 is to be taken with food.

How Pulbo 801 works

Pulbo 801 is an antifibrotic medication. It works by reducing fibrosis (scarring) and swelling in the lungs. This makes breathing easier.

Quick Tips

Pulbo 801 reduces scarring and swelling in the lungs, and helps you breathe better.

It is best to take this medicine with food and at the same time each day.

This medication may make you more sensitive to sun. Use sunscreen and wear protective clothing when outdoors.

Stop smoking during treatment with Pulbo 801 as it can reduce the effect of the treatment.

It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.

It may cause weight loss. Monitor your weight regularly.

Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).

Brief Description

Indication

Idiopathic pulmonary fibrosis (IPF)

Administration

Should be taken with food: Take w/ food to reduce the possibility of nausea & dizziness. Swallow whole w/ water. Take doses at same time each day.

Adult Dose

Idiopathic Pulmonary Fibrosis Initial dose titration Days 1-7: 267 mg (1 capsule) PO TID Days 8-14: 534 mg (2 capsules) PO TID Day 15 and thereafter: 801 mg (3 capsules) PO TID Maintenance dose 801 mg (3 capsules) PO TID with food Not to exceed 2403 mg/day (9 capsules/day) Hepatic impairment Mild-to-moderate (Child Pugh A or B): Use caution; monitor and consider dosage modification or discontinuation as needed Severe (Child Pugh C): Not recommended (not studied)

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Mild, moderate, or severe: Use caution; monitor and consider dosage modification or discontinuation as needed ESRD requiring dialysis: No recommended (not studied)

Contraindication

Hypersensitivity. History of angioedema. Severe hepatic & renal impairment or end stage liver & renal disease. Concomitant use w/ fluvoxamine.

Mode of Action

Precise mechanism by which pirfenidone may work in pulmonary fibrosis has not been established Inhibits transforming growth factor (TGF)-beta, a chemical mediator that controls many cell functions including proliferation and differentiation Also inhibits the synthesis of TNF-alpha, a cytokine that is known to have an active role in inflammation

Precaution

Hepatic function abnormalities, hepatic impairment, photosensitivity reaction or rash, angioedema, dizziness, fatigue & wt loss. May affect ability to drive or operate machinery. Avoid use in pregnancy & lactation.

Side Effect

>10% Nausea (36%),Rash (30%),Upper respiratory tract infection (27%),Diarrhea (26%),Abdominal pain (24%),Headache (22%),Dyspepsia (19%),Dizziness (18%),Vomiting (13%),GERD (11%),Sinusitis (11%) 1-10% Insomnia (10%),Weight decreased (10%),Arthralgia (10%),Photosensitivity (9%),Decreased appetite (8%),Pruritus (8%),Asthenia (6%),Dysgeusia (6%),Noncardiac chest pain (5%),AST/ALT ≥3 x ULN (3.7%) <1% AST/ALT ≥10 x ULN (0.3%)

Pregnancy Category Note

Data in pregnant women are insufficient to inform on drug associated risks for major birth defects and miscarriage.

Interaction

Inhibition of CYP1A2 w/ concomitant grapefruit juice. Increased exposure w/ fluvoxamine & other strong & selective CYP1A2 inhibitors, ciprofloxacin, amiodarone, propafenone. Potential to induce hepatic enzyme production by smoking. Lowered plasma levels w/ omeprazole, rifampicin.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Pulbo 801

Tablet - (801mg)

Opsonin Pharma Limited

Generic: Pirfenidone

Additional Offers

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৳100

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৳80

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৳60

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৳40

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৳20

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Pulbo 801

Medicine Overview of Pulbo 801mg Tablet

Pulbo 801

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