Bestron

Name: Bestron 0.45mg+20mg Tablet
Brand: Incepta Pharmaceuticals Ltd.
SKU: 39858
Price: 727.2 BDT
Availability: InStock
Rating: 4.9 (27 reviews)

Tablet - (0.45mg+20mg)

Incepta Pharmaceuticals Ltd.

Generic: Conjugated Estrogen+Bazedoxifene

৳ 727.20
৳ 800
9% OFF

Medicine Overview of Bestron 0.45mg+20mg Tablet

বাংলা

English

Introduction

Bestron This medication is a combination product containing conjugated estrogens and bazedoxifene (an estrogen agonist/antagonist).Bestron is used by women with a uterus to help reduce symptoms of menopause (such as hot flashes, vaginal dryness) and to prevent bone loss (osteoporosis) after menopause. Conjugated estrogens are hormones which help to decrease menopausal symptoms caused by the body making less estrogen. Bazedoxifene is not a hormone, but works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. The bazedoxifene in this medication helps to preserve bone mass and reduces the risk of...

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Brief Description

Indication

Use to treat moderate to severe vasomotor symptoms associated with menopause, as well as to prevent postmenopausal osteoporosis.

Administration

Take this medication orally with or without food as advised by your doctor, generally once a day. To avoid stomach distress, you can take it with or after a meal. Swallow the tablets whole. Do not break or chew the tablets.

Adult Dose

Should be taken once a day.

Child Dose

Not recommended for use on children.

Renal Dose

It should be used with caution in patients with kidney disease. Dose adjustment of it may be needed. Please consult your doctor.

Contraindication

Women with undiagnosed abnormal uterine bleeding, known, suspected, or past history of breast cancer, known or suspected estrogen-dependent neoplasia, active deep venous thrombosis, pulmonary embolism, or history of these conditions, active arterial thromboembolic disease, hypersensitivity (e.g., anaphylaxis, angioedema) to estrogens, bazedoxifene, or any ingredients, known hepatic impairment, or other known thrombophilic disorders are all contraindications.

Mode of Action

It is a combination of conjugated estrogens and bazedoxifene. Conjugated estrogens and bazedoxifene activate estrogen receptors α and β. Bazedoxifene is an estrogen agonist/antagonist that operates as an agonist in some estrogen-sensitive tissues but an antagonist in others,

Precautions

Estrogen therapy is not recommended for the prevention of cardiovascular disease or dementia. Women with uterus who use unopposed estrogens are more likely to develop endometrial cancer.

Side Effect

High blood pressure, blood clots, liver and thyroid issues, fluid retention, hypocalcemia, dementia, breast lumps, atypical vaginal bleeding, severe headaches, muscle spasms, weakness and weariness, nausea, diarrhea, throat pain, disorientation, and so on.

Pregnancy & Lactation Category Note

Should not be used in women who are or might become pregnant.Breastfeeding mothers should avoid using this product. It is unknown if this medication is excreted in human milk. The delivery of estrogen to nursing moms has been found to reduce the quantity and quality of milk.

Interaction

There were no medication interaction studies done with this pill. Estrogens are partially metabolized by CYP3A4. Concurrent use of this tablet with CYP3A4 inhibitors may increase conjugated estrogen exposure and hence the risk of endometrial hyperplasia.

Storage Conditions

Keep out of the reach of children.Do not store above 30°C. Keep away from light and out of the reach of children. After opening foil pouch, product must be used within 60 days.

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Bestron

Tablet - (0.45mg+20mg)

Incepta Pharmaceuticals Ltd.

Generic: Conjugated Estrogen+Bazedoxifene

৳ 727.20
৳ 800
9% OFF

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.