Renal impairment Severe (CrCl <30 mL/min): Dosage reductions required Prophylaxis in abdominal surgery: 30 mg SC qDay Prophylaxis in hip or knee replacement surgery: 30 mg SC qDay Prophylaxis in medical patients with restricted mobility: 30 mg SC qDay DVT treatment (inpatient or outpatient) coadministered with warfarin: 1 mg/kg SC qDay Non-Q-wave myocardial infarction: 1 mg/kg SC qDay Treatment of acute STEMI (<75 years): 30 mg IV single bolus plus 1 mg/kg SC, THEN 1 mg/kg SC qDay Treatment of acute STEMI (>75 years): No initial bolus; maintenance of 1 mg/kg SC qDay