It is unsafe to consume alcohol with Clofranil 25.
CONSULT YOUR DOCTOR
Clofranil 25 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to y...
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CONSULT YOUR DOCTOR
Clofranil 25 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Clofranil 25 may cause side effects which could affect your ability to drive.
If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Clo...
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CONSULT YOUR DOCTOR
There is limited information available on the use of Clofranil 25 in patients with kidney disease. Please consult your doctor.
Caution should be exercised in patients with underlying kidney disease. Regular monitoring of kidney function test is advis...
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CAUTION
Clofranil 25 should be used with caution in patients with liver disease. Dose adjustment of Clofranil 25 may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable when you are taking this medicine.
Medicine Overview of Clofranil 25mg Tablet
Introduction
Clofranil 25 is a tricyclic antidepressant. It is used in adults to treat Obsessive-Compulsive Disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is un...
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Uses of Clofranil 25
Obsessive-compulsive disorder
Side effects of Clofranil 25
Common
Altered libido
Constipation
Dryness in mouth
Ejaculation disorder
Sleepiness
Difficulty in urination
How to use Clofranil 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clofranil 25 is to be taken with food.
How Clofranil 25 works
Clofranil 25 is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
What if you forget to take Clofranil 25?
If you miss a dose of Clofranil 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
It may take 4 to 6 weeks for Clofranil 25 to start working. Keep taking it as prescribed.
It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Clofranil 25 as it may cause excessive sleepiness.
Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Oral
Adjunct for cataplexy associated with narcolepsy
Adult: Initially, 10 mg daily gradually increased to 10-75 mg daily.
Elderly: Dose reduction ...
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Child Dose
Obsessive-Compulsive Disorder
<10 years: Safety and efficacy not established
>10 years: 25 mg PO qDay initially
Gradually increase to maximum 3...
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Contraindication
Hypersensitivity. Concomitant use of MAOIs; recovery phase following MI, heartblock or other arrhythmias; mania; childn.
Mode of Action
Clomipramine is a potent inhibitor of serotonin re-uptake in the brain. Significant antagonism at cholinergic and ?1-receptors. Weak antagonism at dop...
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Precaution
Cardiovascular insufficiency; narrow-angle glaucoma; urinary retention; history of epilepsy; renal or hepatic dysfunction; electroconvulsive therapy; ...
Pregnancy Category: C
Lactation: distributed in breast milk, do not nurse (AAP states effect on nursing infants is unknown but may be of concern)
Interaction
Barbiturates increase metabolism of tricyclic antidepressants; conversely cimetidine, guanethidine, haloperidol and phenothiazines block the tricyclic...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.