HomeLab TestP-ANCA
Overview
The P-ANCA test (Perinuclear Anti-Cytoplasmic Antibodies) is a blood test used to detect specific antibodies associated with autoimmune diseases, particularly Granulomatosis with Polyangiitis (GPA) and other vasculitis disorders. PANCA antibodies ...
Risk assessment
Ulcerative colitis, Churg Strauss syndrome, Wegener granulomatosis.
Ranges
Normal Range
- Negative Test: P-ANCA is absent (no significant antibody level detected).
- Positive Test: Indicates the presence of P-ANCA. Levels are typically reported as a t...
Test result interpretation
The P-ANC test detects antibodies linked to autoimmune diseases like vasculitis.
• Positive: Suggests conditions like Microscopic Polyangiitis, Eosinophilic Granulomatosis, or inflammatory bowel diseases (e.g., ulcerative colitis).
...
Sample types
Sample Type
- Blood Sample:
- Collected via venipuncture (a standard blood draw).
- Serum or plasma is analyzed in the laboratory.
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Frequently Asked Questions
Which vasculitis has p-ANCA?
What is p-ANCA associated with?
How serious is ANCA vasculitis?
How serious is vasculitis?
Is Churg Strauss P or C ANCA?
P-ANCA
Precision in Autoimmune Diagnosis: Exploring the P-ANCA Test
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Sample Type:
blood
Fasting Required:
No
Description
p-ANCA, or MPO-ANCA, or perinuclear anti-neutrophil cytoplasmic antibodies, are antibodies that stain the material around the nucleus of a neutrophil. They are a special class of anti-neutrophil cytoplasmic antibodies. This pattern occurs because the vast majority of the antigens targeted by ANCAs are highly cationic (positively charged) at pH 7.00.