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Leukin 50

Name: Leukin 50mg Tablet
Brand: Beacon Pharmaceuticals PLC
SKU: 10356
Price: 184 BDT
Availability: InStock
Rating: 4.9 (6 reviews)

Tablet - (50mg)

Beacon Pharmaceuticals PLC

Generic: Mercaptopurine

Safety Advices

বাংলা

English

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Leukin 50. Please consult your doctor.

CONSULT YOUR DOCTOR

Leukin 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

CONSULT YOUR DOCTOR

Leukin 50 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

SAFE

Leukin 50 does not usually affect your ability to drive.

CAUTION

Leukin 50 should be used with caution in patients with kidney disease. Dose adjustment of Leukin 50 may be needed. Please consult your doctor.

CAUTION

Leukin 50 should be used with caution in patients with liver disease. Dose adjustment of Leukin 50 may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Medicine Overview of Leukin 50mg Tablet

Introduction

Leukin 50 is used in the treatment of blood cancer. It shows its working by decreasing the number of red blood cells, which is produced by the body. Leukin 50 can be taken with or without food or you can have it one hour before or 2 hours after the meal. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way...

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Uses of Leukin 50

Blood cancer

Side effects of Leukin 50

Common

Nausea
Vomiting
Rash
Decreased white blood cell count (neutrophils)
Intestinal ulcer
Anemia (low number of red blood cells)
Increased bilirubin in the blood
Low blood platelets
Increased transaminase level in blood
Diarrhea
Loss of appetite

How to use Leukin 50

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leukin 50 may be taken with or without food, but it is better to take it at a fixed time.

How Leukin 50 works

Leukin 50 interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Quick Tips

Leukin 50 is used for the treatment of cancer of the blood.

Take it with or without food.

Do not drive or do anything requiring concentration until you know how it affects you.

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.

Your doctor may get regular blood and urine tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.

Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Brief Description

Indication

Acute lymphatic leukaemia, Crohn's disease

Administration

Should be taken on an empty stomach. Best taken on an empty stomach 1 hr before or 2 hr after meals. Ensure adequate fluid intake.

Adult Dose

Acute Lymphatic Leukemia Induction: 2.5 mg/kg PO qDay; usually 100-200 mg PO qDay in average adult (other agents preferred) May increase by 5 mg/kg/day after 4 weeks Maintenance: 1.5-2.5 mg/kg PO qDay Reduce dose by 75% if concomitant allopurinol administration Crohn's disease Adult: Initially 1-1.5 mg/kg daily, may increase to 125 mg daily. Hepatic impairment: Dosage may need to be reduced.

Child Dose

Acute Lymphatic Leukemia Starting dose: 1.25-2.5 mg/kg (50-75 mg/m²) PO qDay Maintenance: 1.5-2.5 mg/kg PO qDay in combination with methotrexate

Renal Dose

Renal Impairment: Dosage may need to be reduced.

Contraindication

Pregnancy and lactation. Prior resistance to mercaptopurine or thioguanine; severe liver disease; severe bone marrow suppression.

Mode of Action

Mercaptopurine is a purine antagonist which is converted intracellularly into its active nucleotides, including thioinosinic acid. The nucleotides inhibit several reactions which ultimately interferes with nucleic acid synthesis and prevents the formation of RNA and DNA.

Precaution

Hepatic or renal dysfunction; monitor hepatic function periodically. Mercaptopurine is potentially carcinogenic. Thiopurine S-methyl transferase (TPMT) deficiency; porphyria. Lactation: not known if excreted in breast milk, do not nurse

Side Effect

>10% Elevated LFT's (15%) 1-10% Nausea (10%),Vomiting (10%),Stomatitis (3-10%),Thrombocytopenia (3-10%),Rash (1-3%),Diarrhea (1-3%),Dizziness (1-3%),Alopecia (1-3%),Leukopenia (1-3%) Frequency Not Defined Fatigue,Anorexia,Headache,Chills and fever,Chest pain,Mucositis,Upper respiratory infection,Cough,Ulceration of intestine,Ulcerative stomatitis,Myelosuppressionm,Decreased hematocrit,Hepatotoxicity,Decreased resistance to infections,Hyperuricemia,Nephrotoxicity,Increased risk of pancreatitis in pts with IBD,Hyperpigmentation of skin,Arthralgias,Eye discomfort,Tinnitus Potentially Fatal: Myelosuppression; hepatotoxicity, cholestatic jaundice.

Interaction

Anticoagulant action of warfarin may be inhibited by mercaptopurine. Enhanced toxicity with myelosuppressive drugs. Potentially Fatal: Effects enhanced by allopurinol (reduce dose of mercaptopurine). Other hepatotoxic drugs (e.g. doxorubicin) potentiate toxicity.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Leukin 50

Tablet - (50mg)

Beacon Pharmaceuticals PLC

Generic: Mercaptopurine

Additional Offers

Cashback

৳100

For purchasing above ৳5000+

Cashback

৳80

For purchasing above ৳4000+

Cashback

৳60

For purchasing above ৳3000+

Cashback

৳40

For purchasing above ৳2000+

Cashback

৳20

For purchasing above ৳1000+

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Leukin 50

Medicine Overview of Leukin 50mg Tablet

Leukin 50

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