It is not known whether it is safe to consume alcohol with Leukin 50. Please consult your doctor.
CONSULT YOUR DOCTOR
Leukin 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Leukin 50 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
SAFE
Leukin 50 does not usually affect your ability to drive.
CAUTION
Leukin 50 should be used with caution in patients with kidney disease. Dose adjustment of Leukin 50 may be needed. Please consult your doctor.
CAUTION
Leukin 50 should be used with caution in patients with liver disease. Dose adjustment of Leukin 50 may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.
Medicine Overview of Leukin 50mg Tablet
Introduction
Leukin 50 is used in the treatment of blood cancer. It shows its working by decreasing the number of red blood cells, which is produced by the body.
Leukin 50 can be taken with or without food or you can have it one hour before or 2 hours after the ... Show more
Uses of Leukin 50
Blood cancer
Side effects of Leukin 50
Common
Nausea
Vomiting
Rash
Decreased white blood cell count (neutrophils)
Intestinal ulcer
Anemia (low number of red blood cells)
Increased bilirubin in the blood
Low blood platelets
Increased transaminase level in blood
Diarrhea
Loss of appetite
How to use Leukin 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leukin 50 may be taken with or without food, but it is better to take it at a fixed time.
How Leukin 50 works
Leukin 50 interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
Quick Tips
Leukin 50 is used for the treatment of cancer of the blood.
Take it with or without food.
Do not drive or do anything requiring concentration until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood and urine tests done to monitor your blood cells, kidney and liver function during treatment with this med ... Show more
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Brief Description
Indication
Acute lymphatic leukaemia, Crohn's disease
Administration
Should be taken on an empty stomach. Best taken on an empty stomach 1 hr before or 2 hr after meals. Ensure adequate fluid intake.
Adult Dose
Acute Lymphatic Leukemia
Induction: 2.5 mg/kg PO qDay; usually 100-200 mg PO qDay in average adult (other agents preferred)
May increase by 5 mg/kg ... Show more
Child Dose
Acute Lymphatic Leukemia
Starting dose: 1.25-2.5 mg/kg (50-75 mg/m²) PO qDay
Maintenance: 1.5-2.5 mg/kg PO qDay in combination with methotrexate
Renal Dose
Renal Impairment: Dosage may need to be reduced.
Contraindication
Pregnancy and lactation. Prior resistance to mercaptopurine or thioguanine; severe liver disease; severe bone marrow suppression.
Mode of Action
Mercaptopurine is a purine antagonist which is converted intracellularly into its active nucleotides, including thioinosinic acid. The nucleotides inh ... Show more
Precaution
Hepatic or renal dysfunction; monitor hepatic function periodically. Mercaptopurine is potentially carcinogenic. Thiopurine S-methyl transferase (TPMT ... Show more
Side Effect
>10%
Elevated LFT's (15%)
1-10%
Nausea (10%),Vomiting (10%),Stomatitis (3-10%),Thrombocytopenia (3-10%),Rash (1-3%),Diarrhea (1-3%),Dizziness (1- ... Show more
Interaction
Anticoagulant action of warfarin may be inhibited by mercaptopurine. Enhanced toxicity with myelosuppressive drugs.
Potentially Fatal: Effects enha ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.