Caution is advised when consuming alcohol with Locol 10. Please consult your doctor.
UNSAFE
Locol 10 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Locol 10 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SAFE
Locol 10 does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Locol 10 is safe to use in patients with kidney disease. No dose adjustment of Locol 10 is recommended.
However, inform your doctor if you have any underlying kidney disease.
CAUTION
Locol 10 should be used with caution in patients with liver disease. Dose adjustment of Locol 10 may be needed. Please consult your doctor.
Use of Locol 10 is not recommended in patients with severe liver disease and active liver disease.
Medicine Overview of Locol 10mg Tablet
Introduction
Locol 10 belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart at ... Show more
Uses of Locol 10
High cholesterol
Prevention of heart attack
Side effects of Locol 10
Common
Constipation
Headache
Muscle pain
How to use Locol 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Locol 10 may be taken with or without food, but it is better to take it at a fixed time.
How Locol 10 works
Locol 10 is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL) and triglycerides, raising the level of "good" cholesterol ( ... Show more
What if you forget to take Locol 10?
If you miss a dose of Locol 10, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses within 12 hour.
Quick Tips
In general, Locol 10 is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of ... Show more
Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, ... Show more
Do not take Locol 10 if you are pregnant, planning a pregnancy or breastfeeding.
Brief Description
Indication
Oral
Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia
Adult: Initially, 10 or 20 mg once daily, m ... Show more
Administration
May increase risk of myopathy and rhabdomyolysis w/ CYP3A4 potent inhibitor (e.g. HIV or HCV protease inhibitors, itraconazole, clarithromycin), fenof ... Show more
Adult Dose
Patients who consume substantial quantities of alcohol. History of liver disease. Patients with risk factors for myopathy or rhabdomyolysis. Hypothyro ... Show more
Renal Dose
Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate. This results in the inductio ... Show more
Contraindication
Oral
Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia
Child: Heterozygous familial hypercholester ... Show more
Mode of Action
Atorvastatin can be administered as a single dose at any time of the day, with or without food. Avoid excessive consumption (>1 L/day) of grapefruit j ... Show more
Precaution
Primary hypercholesterolemia (heterozygous familial and nonfamilial), Mixed Dyslipidemia, Homozygous familial hypercholesterolemia, Hypertriglyceride ... Show more
Side Effect
Renal Insufficiency: Renal disease does not affect the plasma concentrations or LDL-C reduction of atorvastatin; thus, dosage adjustment in patients w ... Show more
Pregnancy Category Note
>10%
Diarrhea (5-14%),Nasopharyngitis (4-13%),Arthralgia (4-12%)
1-10%
Insomnia (1-5%),Urinary tract infection (4-8%),Nausea (4-7%),Dyspepsia (3- ... Show more
Interaction
Hypersensitivity, active liver disease or unexplained persistent elevations of serum transaminase, porphyria, pregnancy, lactation.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.