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Nexito 5
Sun Pharmaceutical (Bangladesh) Ltd.
Generic: Escitalopram
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Nexito 5.
CONSULT YOUR DOCTOR
Nexito 5 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Nexito 5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Nexito 5 may cause side effects which could affect your ability to drive.
CAUTION
Nexito 5 should be used with caution in patients with severe kidney disease. Dose adjustment of Nexito 5 may be needed. Please consult your doctor.
CAUTION
Nexito 5 should be used with caution in patients with liver disease. Dose adjustment of Nexito 5 may be needed. Please consult your doctor.
Medicine Overview of Nexito 5mg Tablet
Introduction
Nexito 5 is widely prescribed to treat depression and other mental health conditions like anxiety, panic disorder, and obsessive-compulsive disorder. It is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). Nexito 5 helps many people to recover from depression by improving their mood and relieving anxiety and tension. It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Your doctor may start you on a lower dose and increase it gradually. Do not...
... Show moreUses of Nexito 5
- Depression
- Anxiety
- Panic disorder
- Obsessive-compulsive disorder
Side effects of Nexito 5
Common
- Anorgasmia (decreased orgasm) in women
- Decreased libido
- Delayed ejaculation
- Fatigue
- Increased sweating
- Insomnia (difficulty in sleeping)
- Nausea
- Sleepiness
How to use Nexito 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nexito 5 may be taken with or without food, but it is better to take it at a fixed time.
How Nexito 5 works
Nexito 5 is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of anxiety, panic attacks and obsessive-compulsive disorders.
What if you forget to take Nexito 5?
If you miss a dose of Nexito 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Take it in the morning since it can keep you awake if taken late at night.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- It has a lower chance of causing sexual dysfunction than other similar medications.
- The addiction or dependence potential of Nexito 5 is very less.
- Do not stop taking the medication suddenly without talking to your doctor first.
- Some people can develop dizziness or drowsiness after taking this medicine. Do not drive or do anything that requires mental focus until you know how this medicine affects you
Brief Description
Indication
Major depressive disorder, Depression, Panic disorder, Obsessive compulsive disorder, Anxiety disorder
Administration
May be taken with or without food.
Adult Dose
Oral
Anxiety; Depression; Obsessive compulsive disorder
Adult: 10 mg once daily, increased after at least a wk if needed. Max: 20 mg once daily.
Panic disorder with or without agoraphobia
Adult: Initially, 5 mg once daily, increased after a wk to 10 mg once daily. Max: 20 mg daily.
Elderly: Half the adult dose.
Hepatic impairment: Mild to moderate: Initially, 5 mg daily, increased to 10 mg daily after 2 wk if needed. Severe: More careful dose titration needed.
Child Dose
Major Depressive Disorder
12 years: 10 mg PO qDay; may increase dose after at least 3 weeks; not to exceed 20 mg/day
Contraindication
Concomitant use with or within 2 wk of MAOI withdrawal.
Mode of Action
Escitalopram selectively inhibits CNS neuronal re-uptake of serotonin (5-HT) and potentiates serotonergic activity. It has minimal effects on norepinephrine and dopamine neuronal re-uptake.
Precaution
History of mania or seizure disorders; work requiring mental alertness; renal and hepatic impairment; pregnancy, lactation; withdraw gradually.
Lactation
Excreted in breast milk; consider risk/benefit ratio
Side Effect
>10%
Headache (24%),Nausea (18%),Ejaculation disorder (9-14%),Somnolence (4-13%),Insomnia (7-12%)
1-10%
Xerostomia (4-9%),Constipation (3-6%),Fatigue (2-8%),Libido decrease (3-7%),Anorgasmia (2-6%),Flatulence (2%),Toothache (2%),Weight gain (1%),Menstrual disorder (2%),Neck/shoulder pain (3%),Rhinitis (5%),Flu-like syndrome (5%),Ejaculation disorder (9-14%)
<1%
Arthralgia,Abdominal pain,Abnormal bleeding,Abnormal dreams,Allergy,Blurred vision,Bronchitis,Chest pain,Constipation,Decreased appetite,Decreased concentration,Disrupts platelets/hemostasis,Dizziness,Dyspepsia,Fever,Heartburn,Hot flashes,Impotence,Irritability,Jaw stiffness,Lethargy,Lightheadedness,Menstrual disorder,Hypertension,Palpitations,Migraine,Myalgia,Paresthesia,Rash,Sweating,Tinnitus,Tremor,Urinary frequency,Urinary tract infection,Vertigo,Vomiting,Yawning
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies in pregnant women; therefore, use during pregnancy only if the potential benefit justifies the potential risk to the fetus In some cases, the clinical picture is consistent with serotonin syndrome Effect on labor and delivery in humans is unknown Neonates exposed to escitalopram and other SSRIs/SNRIs Neonates exposed to SSRIs/SNRIs late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding Such complications can arise immediately upon delivery Reported clinical findings include respiratory distress, cyanosis, apnea, seizures, temperature instability, feeding difficulty, vomiting, hypoglycemia, hypotonia, hypertonia, hyperreflexia, tremor,...
... Show moreInteraction
Increased risk of bleeding when used with aspirin, NSAIDs or drugs that affect coagulation. Serum levels may be reduced by CYP2C19 inducers (e.g. carbamazepine, rifampin, phenytoin) or CYP3A4 inducers (e.g. nafcillin, nevirapine). Serum levels may also be increased by CYP2C19 inhibitors (e.g. fluconazole, fluvoxamine, omeprazole) or CYP3A4 inhibitors (e.g. azole antifungals, clarithromycin). May increase serum levels of desipramine or metoprolol. Increased risk of serotonin syndrome when used with linezolid or sibutramine. Escitalopram may enhance the sedative effects of alcohol. Potentially Fatal: Concomitant administration with MAOIs may lead to serious or fatal reactions; should not be started until at least 2...
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