Caution is advised when consuming alcohol with Apilast. Please consult your doctor.
CONSULT YOUR DOCTOR
Apilast may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Apilast during breastfeeding is not available. Please consult your doctor.
SAFE
Apilast does not usually affect your ability to drive.
CAUTION
Apilast should be used with caution in patients with severe kidney disease. Dose adjustment of Apilast may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Apilast is safe to use in patients with liver disease. No dose adjustment of Apilast is recommended.
Medicine Overview of Apilast 10mg Tablet
Introduction
Apilast is used in the treatment of moderate to severe plaque psoriasis which is a type of skin condition. This medicine is used when other conventional treatments cannot be used or if the patient is not responsive or intolerant to any of these treat ... Show more
Uses of Apilast
Plaque psoriasis
Side effects of Apilast
Common
Diarrhea
Nausea
Vomiting
How to use Apilast
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apilast may be taken with or without food, but it is better to take it at a fixed time.
How Apilast works
Apilast is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of ... Show more
Quick Tips
Apilast is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
Monitor your weight regularly as Apilast may cause weight loss.
Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
Brief Description
Indication
Active psoriatic arthritis, moderate to severe plaque psoriasis
Administration
To reduce risk of GI symptoms associated with initial therapy, titrate to recommended dose (30 mg PO BID) according to the dosage schedules listed abo ... Show more
Adult Dose
Active psoriatic arthritis, moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
To reduce risk of gastroint ... Show more
Renal Dose
Severe renal impairment (CrCl <30 mL/min): Reduce dose to 30 mg PO qDay
Mild-to-moderate renal impairment: No dosage adjustment required
Contraindication
Known hypersensitivity to apremilast.
Mode of Action
Apremilast is an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP). PDE4 inhibition resul ... Show more
Precaution
Apremilast is associated with an increase in adverse reactions of depression. Before using, evaluate patient for history of depression and/or suicidal ... Show more
Side Effect
1-10%
Diarrhea (7.7-9.3%),Nausea (7.4-8.9%),Headache (4.8-5.9%),Upper respiratory tract infection (0.6-3.9%),Vomiting (0.8-3.2%),Nasopharyngitis (0.2 ... Show more
Pregnancy Category Note
Pregnancy
Available pharmacovigilance data use in pregnant women have not established a drug-associated risk of major birth defects, miscarriage or a ... Show more
Interaction
Coadministration with strong CYP inducers (eg, rifampin, carbamazepine, phenobarbital phenytoin) may occur and result in a loss of efficacy of apremil ... Show more
ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.