Generic: Hydrocortisone + Neomycin Sulphate + Polymixin B E/E prep
Medicine Overview of Polymix H Eye Drop
বাংলা
English
Indication
Ocular inflammation, Otitis externa
Adult Dose
Ophthalmic
Ocular inflammation with suspected or confirmed bacterial infection
Adult: 1-2 drops every 3-4 hrly as indicated.
Otic/Aural
Otitis externa
Adult: As combination containing neomycin sulfate 3.5 mg as neomycin base, polymyxin B sulf ... Show more
Child Dose
Otic/Aural
Otitis externa
Child: 2-16 yr: As combination containing neomycin sulfate 3.5 mg as neomycin base, polymyxin B sulfate 10,000 units, hydrocortisone 10 mg (1%) per ml:
Instill 3 drops into affected ear 3-4 times daily; instill drop with ... Show more
Contraindication
Hypersensitivity to aminoglycosides and any of its components. Pre-existing nerve deafness. TB, fungal or viral infections. Do not use in external eardrum if tympanic membrane is perforated.
Mode of Action
Neomycin, an aminoglycoside with spectrum similar to gentamicin, binds to the 30S subunits of the bacterial ribosome, inhibiting protein synthesis and thereby disrupting DNA synthesis. It is active against many Gram-negative aerobes and some strains ... Show more
Precaution
Ophthalmic: Glaucoma; monitor intraocular pressure regularly if used for >10 days.
Otic: Limit use to ≤10 days to reduce risk of ototoxicity. May cause burning and stinging if product enters the middle ear.
Additive toxicity with neurotoxic, ototoxic or nephrotoxic drugs. Increased neuromuscular blockade and possibly respiratory depression with neuromuscular blocking agents if significant amounts of neomycin absorbed significantly.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.