Consuming alcohol while taking Pylotrip may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pylotrip may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. ...

Pylotrip is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Pylotrip may cause side effects which could affect your ability to drive. Pylotrip can have side effects and the symptoms (such as allergic reactions, dizziness and convulsions) may make you unfit to drive.

Pylotrip should be used with caution in patients with kidney disease. Dose adjustment of Pylotrip may be needed. Please consult your doctor. Use of this medicine is not recommended in patients with severe kidney disease.

Pylotrip is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pylotrip may not be needed in these patients. Please consult your doctor.