Repace 25 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Repace 25 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CONSULT YOUR DOCTOR
It is not known whether Repace 25 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
SAFE IF PRESCRIBED
Repace 25 is safe to use in patients with kidney disease. No dose adjustment of Repace 25 is recommended.
However, talk to your doctor if you have any underlying kidney disease. Regular monitoring of blood pressure is recommended for better dose adjustment.
CAUTION
Repace 25 should be used with caution in patients with liver disease. Dose adjustment of Repace 25 may be needed. Please consult your doctor.
Use of Repace 25 is not recommended in patients with severe liver disease.
Medicine Overview of Repace 25mg Tablet
Introduction
Repace 25 is a medicine used to treat high blood pressure and heart disease. Lowering blood pressure helps to prevent future heart attack and stroke. This medicine is also effective in preserving kidney function in patients with diabetes.
Repace 25 ... Show more
Uses of Repace 25
Hypertension (high blood pressure)
Heart failure
Prevention of heart attack and stroke
Side effects of Repace 25
Common
Dizziness
Decreased blood pressure
Hypoglycemia (low blood glucose level)
Increased potassium level in blood
Increased blood urea
How to use Repace 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Repace 25 may be taken with or without food, but it is better to take it at a fixed time.
How Repace 25 works
Repace 25 is an angiotensin receptor blocker (ARB). It relaxes the blood vessel by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure, allowing the blood to flow more smoothly to different organ ... Show more
What if you forget to take Repace 25?
If you miss a dose of Repace 25, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
Take it at the same time every day to help you remember to take it.
It can make you feel dizzy for the first few days. Rise slowly if you have been sitting or lying down for a long time.
Your doctor may get regular tests done to monitor the level of urea, creatinine, and potassium in your blood.
Avoid taking anti-inflammatory medicines such as ibuprofen along with this medicine without consulting your doctor.
Do not take Repace 25 if you are pregnant or breastfeeding.
Do not stop taking it suddenly without talking to your doctor.
Brief Description
Indication
Diabetic nephropathy, Hypertension, Stroke risk reduction of hypertensive or LVH patients, Heart Failure, Hypertensive Patients with Left Ventricular ... Show more
Administration
May be taken with or without food.
Adult Dose
Oral
Hypertension
Adult: 50 mg once daily, may increase to 100 mg/day as single dose or in 2 divided doses if needed. Patients w/ intravascular volu ... Show more
Child Dose
Hypertension
<6 years: Safety and efficacy not established
Child: >6 yr 20-50 kg: Initially, 0.7 mg/kg. Max: 50 mg/day;
>50 kg: Initially, 1.4 m ... Show more
Renal Dose
Renal impairment: CrCl <20 ml/min: Initially 25 mg once daily.
Contraindication
Losartan potassium is contraindicated in patients who are hypersensitive to the active ingredient or any component of the drug. Concomitant use w/ ali ... Show more
Mode of Action
Losartan is an angiotensin II receptor antagonist. It selectively and competitively blocks the vasoconstricting and aldosterone-secreting effects of a ... Show more
Precaution
Volume-depleted patients including patients on high-dose diuretics. Patients w/ bilateral renal artery stenosis , aortic or mitral stenosis. Renal and ... Show more
Side Effect
>10%
Fatigue (14%),Hypoglycemia (14%),Anemia (14%),Urinary tract infection (UTI) (13%),Chest pain (12%),Weakness (14%),Diarrhea (2-15%),Cough; incide ... Show more
Pregnancy Category Note
Pregnancy Categories C (first trimester) and D (second and third trimesters).
Interaction
May decrease plasma levels / fluconazole and rifampicin. May increase serum lithium levels and toxicity. May antagonise hypotensive effect and increas ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.