Caution is advised when consuming alcohol with Restat 5. Please consult your doctor.
UNSAFE
Restat 5 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Restat 5 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SAFE
Restat 5 does not usually affect your ability to drive.
CAUTION
Restat 5 should be used with caution in patients with kidney disease. Dose adjustment of Restat 5 may be needed. Please consult your doctor.
Use of Restat 5 is not recommended in patients with severe kidney disease.
CAUTION
Restat 5 should be used with caution in patients with liver disease. Dose adjustment of Restat 5 may be needed. Please consult your doctor.
Use of Restat 5 is not recommended in patients with severe liver disease and active liver disease.
Medicine Overview of Restat 5mg Tablet
Introduction
Restat 5 belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart at ... Show more
Uses of Restat 5
High cholesterol
Prevention of heart attack and stroke
Side effects of Restat 5
Common
Muscle pain
Weakness
Headache
Abdominal pain
How to use Restat 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Restat 5 may be taken with or without food, but it is better to take it at a fixed time.
How Restat 5 works
Restat 5 is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL).
What if you forget to take Restat 5?
If you miss a dose of Restat 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses within 12 hours.
Quick Tips
Restat 5 treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exe ... Show more
In general, Restat 5 is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of ... Show more
Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, ... Show more
Do not take Restat 5 if you are pregnant, planning a pregnancy or breastfeeding.
Brief Description
Indication
Hyperlipidaemias, Primary hypercholesterolaemia (heterozygous familial hypercholesterolaemia), mixed dyslipidaemia, homozygous familial hypercholester ... Show more
Administration
May be taken with or without food.
Adult Dose
Oral
Hypercholesterolemia, Hypertriglyceridemia, hyperlipidemia, mixed dyslipidemiaProphylaxis of cardiovascular events in high-risk patients
Adult: ... Show more
Child Dose
Oral
Child
Heterozygous familial hypercholesterolaemia: >10 yr Initially, 5 mg once daily, may be adjusted at intervals of at least 4 wk.
Max: 20 ... Show more
Renal Dose
Renal impairment
Severe (CrCl <30 mL/min/1.73m²) and not on hemodialysis: Decrease starting dose to 5 mg PO qDay; not to exceed 10 mg PO qDay
CrCl>3 ... Show more
Contraindication
Severe renal impairment, active liver disease, unexplained persistent elevations of serum transaminases; hypersensitivity. Pregnancy, lactation.
Mode of Action
Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis. It increases the number ... Show more
Precaution
Patients w/ predisposing factors for myopathy (e.g. untreated hypothyroidism, renal impairment), history of chronic liver disease and alcoholism. Moni ... Show more
Side Effect
>10%
Myalgia (3-13%)
1-10%
Arthralgia (10%),Diabetes mellitus, new onset (3%),Pharyngitis (9%),Headache (6%),Asthenia (up to 5%),Dizziness (4%),C ... Show more
Interaction
May increase serum levels of warfarin and oral contraceptives. May increase serum levels w/ itraconazole, HIV protease inhibitors. May decrease serum ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.