Consuming alcohol with Rofecin 250mg IM does not cause any harmful side effects.
SAFE IF PRESCRIBED
Rofecin 250mg IM is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
CAUTION
Rofecin 250mg IM should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
UNSAFE
Rofecin 250mg IM may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Rofecin 250mg IM is safe to use in patients with kidney disease. No dose adjustment of Rofecin 250mg IM is recommended.
However, inform your doctor if you have any underlying kidney disease.
CAUTION
Rofecin 250mg IM should be used with caution in patients with severe liver disease. Dose adjustment of Rofecin 250mg IM may be needed. Please consult your doctor.
Dose adjustment of Rofecin 250mg IM is not recommended in patients with mild to moderate liver disease.
Medicine Overview of Rofecin 250mg IM 250mg/vial Injection
Introduction
Rofecin 250mg IM is an antibiotic belonging to the cephalosporin group, which is used to treat bacterial infections in your body. It is effective in infections of the brain (e.g., meningitis), lungs (e.g., pneumonia), ear, urinary tract, skin & soft ... Show more
Uses of Rofecin 250mg IM
Bacterial infections
Side effects of Rofecin 250mg IM
Common
Abnormal liver function tests
Diarrhea
Rash
How to use Rofecin 250mg IM
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Rofecin 250mg IM works
Rofecin 250mg IM is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
What if you forget to take Rofecin 250mg IM?
If you miss a dose of Rofecin 250mg IM, please consult your doctor.
Quick Tips
Your doctor has prescribed Rofecin 250mg IM to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to tr ... Show more
Discontinue Rofecin 250mg IM and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficult ... Show more
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find bloo ... Show more
Brief Description
Indication
Pneumonia, Meningitis, Acute otitis media, Lyme disease, Typhoid fever, Otitis media, Pelvic inflammatory disease, Septicemia, Skin and Skin-Structure ... Show more
Administration
IV/IM Administration
IV: Infuse intermittently over 30 minutes
IM: Inject deep into large muscle mass
Adult Dose
Susceptible infections IV/IM 1-2 g/day, up to 4 g/day for severe infections.
Intra-abdominal Infections
Complicated, mild-to-moderate, community ... Show more
Child Dose
Children: IV, IM: 50–75 mg/kg/day, max 2 g/day q24h
50 mg/kg, max 1 g, 1–3 doses IM for AOM q24h
100 mg/kg/day for meningitis, max 4 g/day q12h
... Show more
Renal Dose
Renal impairment:
CrCl (ml/min)
<10 Max: 2 g daily.
Contraindication
Hypersensitivity to cephalosporins; hyperbilirubinaemic neonates. Do not use calcium or calcium-containing solutions or products with or within 48 hr ... Show more
Mode of Action
Ceftriaxone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis i ... Show more
Precaution
History of penicillin allergy; severe renal impairment; pregnancy and lactation; superinfection.
Lactation: Drug enters breast milk in low concentr ... Show more
Side Effect
>10%
Induration after IM injection (5-17%)
1-10%
Eosinophilia (6%),Thrombocytosis (5%),Diarrhea (3%),Elevated hepatic transaminases (3%),Leukopen ... Show more
Pregnancy Category Note
Pregnancy category: B
Lactation: Drug enters breast milk in low concentrations; use with caution
Interaction
May increase nephrotoxicity of aminoglycosides. May diminish therapeutic effect of BCG, typhoid vaccine, Na picosulfate. May increase anticoagulant ef ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.