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Sotalex 80
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Sotalol Hydrochloride
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Sotalex 80.
SAFE IF PRESCRIBED
Sotalex 80 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CONSULT YOUR DOCTOR
Sotalex 80 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Sotalex 80 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Sotalex 80 should be used with caution in patients with kidney disease. Dose adjustment of Sotalex 80 may be needed. Please consult your doctor.
Use of Sotalex 80 is not recommended in patients with serious kidney disease.
SAFE IF PRESCRIBED
Sotalex 80 is safe to use in patients with liver disease. No dose adjustment of Sotalex 80 is recommended.
Medicine Overview of Sotalex 80mg Tablet
Introduction
Sotalex 80 is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia. It is an anti-arrhythmic type of medicine and rapidly restores your heart to a steady and regular rhythm. Sotalex 80 should be taken as advised by your doctor. It may be taken with or without food. Continuous monitoring of blood pressure and heart rate may be needed while taking this medicine. It is important that you keep taking it until your doctor decides it is safe to stop it. If you stop taking this medicine, you may get dangerous uneven heartbeats, which...
... Show moreUses of Sotalex 80
- Arrhythmia
Side effects of Sotalex 80
Common
- Dizziness
- Fatigue
- Slow heart rate
- Breathlessness
- Weakness
How to use Sotalex 80
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sotalex 80 may be taken with or without food, but it is better to take it at a fixed time.
Avoid Sotalex 80 with dairy products such as milk, cheese, curd, butter, paneer and ice cream.
How Sotalex 80 works
Sotalex 80 is an anti-arrhythmic medication. It regulates heart beat by blocking abnormal electrical signals in the heart.
What if you forget to take Sotalex 80?
If you miss a dose of Sotalex 80, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Your doctor may get regular blood tests done to monitor sodium and potassium level, blood sugar level, kidney function, and lung function while you are taking this medicine.
- Notify your doctor if you have any heart or kidney problem.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Please remind your doctor you are taking this medicine every time you visit him and ask him if the medicine can be stopped.
Brief Description
Indication
Supraventricular arrhythmias, Ventricular arrhythmias, Acute arrhythmias
Administration
Should be taken on an empty stomach. Take 1-2 hr before meals.
Adult Dose
Oral
Supraventricular and ventricular arrhythmias
Adult: Initially, 80 mg/day as single or in 2 divided doses, increased gradually every 2-3 days. Usual dose: 160-320 mg/day in 2 divided doses.
Life-threatening ventricular arrhythmias
Adult: Initially, 80 mg bid, increased gradually every 3 days to 240-320 mg/day in divided doses if needed. Maintenance: 160-320 mg/day in divided doses. Max: 480-640 mg in divided doses.
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
30-60 Half the usual dose.
10-30 Quarter the usual dose.
<10 Not recommended.
Contraindication
Bronchial asthma or history of COPD, sick sinus syndrome, symptomatic sinus bradycardia, cardiogenic shock. 2nd and 3rd degree AV block, untreated phaeochromocytoma, torsades de pointes, congenital or acquired long QT syndromes, uncontrolled cardiac failure, cardiogenic shock, metabolic acidosis, hypotension, severe peripheral arterial disease, Raynaud's disease, anaesthesia that causes myocardial depression. Renal impairment (CrCl <10 mL/min). Concomitant use w/ Ca channel blockers (e.g. verapamil and diltiazem).
Mode of Action
Sotalol is a non-cardioselective beta-blocker. It increases sinus cycle length, slows heart rate, decreases AV nodal conduction and increases AV nodal refractoriness. It also prolongs AV monophasic action potentials. However, it lacks intrinsic sympathomimetic and membrane-stabilising properties.
Precaution
Patients w/ well-compensated heart failure, myasthenia gravis, DM, 1st degree AV block. May mask symptoms of hyperthyroidism and hypoglycaemia. May worsen psoriasis. Patients undergoing major surgery requiring general anaesth. Avoid abrupt withdrawal as it may precipitate thyroid storm and exacerbate angina and MI. Renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor BP, heart rate, serum creatinine; Mg and K levels.
Side Effect
>10%
Dyspnea (21%),Dizziness (20%),Fatigue (20%),Bradycardia (16%),Chest pain (16%),Palpitation (14%),Weakness (13%),Lightheadedness (12%)
1-10%
Nausea/vomiting (10%),Edema (8%),Headache (8%),Sleep disturbances (8%),Abnormal ECG (7%),Diarrhea (7%),Extremity pain (7%),Hypotension (6%),Mental confusion (6%),Congestive heart failure (5%),Itching/rash (5%),Syncope (5%),Anxiety (4%),Depression (4%),Torsades de pointes or new ventricular tachycardia/fibrillation in patients with supraventricular arrhythmia (4%),Peripheral vascular disorders (3%),Impotence (2%),Proarrhythmic effect (1.5-2%),Torsades de pointes with history of sustained ventricular tachycardia (1%)
Frequency Not Defined
Catechol hypersensitivity after abrupt withdrawal,Increased insulin requirement in diabetics
Potentially Fatal: Polymorphic ventricular tachycardia (very rare). Rebound hypertension.
Interaction
May increase risk of bradycardia w/ digoxin. May increase risk of arrhythmias w/ diuretics. May potentiate rebound HTN w/ clonidine. May prolong refractoriness w/ disopyramide, quinidine, procainamide, amiodarone and bepridil. May prolong QT interval w/ TCAs, phenothiazines, terfenadine and astemizole. Increased risk of torsades de pointes w/ K-depleting diuretics, erythromycin IV, halofantrine, pentamidine, and quinolones. May prolong neuromuscular blockade of tubocurarine. May reduce response to insulin and oral hypoglycaemics.
Potentially Fatal: Additive effect on AV conduction and ventricular function w/ verapamil and diltiazem.
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