Insomnia
Recommended starting dose: 10 mg PO taken no more than once per night and within 30 minutes of going to bed.
Not to exceed 20 mg once daily.
Hepatic impairment
Mild-to-moderate: No dosage adjustment required
Severe: Not recommended
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment: No dosage adjustment required
Contraindication
Hypersensitivity. Narcolepsy
Mode of Action
Orexin receptor antagonist; orexin, also called hypocretin, is a neurotransmitter that regulates arousal, wakefulness, and appetite
Blocking the binding of wake-promoting neuropeptides orexin A and orexin B to receptors OX1R and OX2R is thought to s ... Show more
Precaution
Can impair daytime wakefulness; CNS depressant effects can last for up to several days after discontinuation
Can impair driving skills and may increase the risk of falling asleep while driving
Dosage adjustments of suvorexant and concomitant CNS de ... Show more
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.