Avastin is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Avastin is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SAFE
Avastin does not usually affect your ability to drive.
CAUTION
Avastin should be used with caution in patients with severe kidney disease. Dose adjustment of Avastin may be needed. Please consult your doctor.
CAUTION
Avastin should be used with caution in patients with liver disease. Dose adjustment of Avastin may be needed. Please consult your doctor.
Use of Avastin is not recommended in patients with severe liver disease and active liver disease.
Medicine Overview of Avastin 10mg Tablet
Introduction
Avastin belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart att ... Show more
Uses of Avastin
High cholesterol
Prevention of heart attack and stroke
Side effects of Avastin
Common
Abdominal pain
Constipation
Headache
Upper respiratory tract infection
How to use Avastin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avastin may be taken with or without food, but it is better to take it at a fixed time.
How Avastin works
Avastin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL) and triglycerides, raising the level of "good" cholesterol (H ... Show more
What if you forget to take Avastin?
If you miss a dose of Avastin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose
Quick Tips
It should be taken in the evening after dinner and before sleeping.
It should be taken in addition to regular exercise and low-fat diet to lower levels of fat in the blood.
Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of ... Show more
Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, ... Show more
Do not take Avastin if you are pregnant, planning a pregnancy or breastfeeding.
Brief Description
Indication
Hyperlipidaemias, stroke prevention
Administration
May be taken with or without food.
Adult Dose
Oral
Hyperlipidaemias, Hypercholesterolemia
Adult: Initially, 10-20 mg once daily.
Patients w/ high CV risk or require a large reduction in choles ... Show more
Child Dose
Child
Heterozygous familial hypercholesterolaemia:
10-17 yr Initially, 10 mg once daily May increase at intervals of 4 wk to max 40 mg/day.
All d ... Show more
Renal Dose
Renal impairment: Mild to moderate: No dosage adjustment needed. Severe: Initially, 5 mg once daily w/ close monitoring.
Contraindication
Acute liver disease or unexplained persistent elevations of serum transaminases. Patients of Chinese descent should not take simvastatin 80 mg/day w/ ... Show more
Mode of Action
Simvastatin, an antilipemic agent is a competitive inhibitor of HMG-CoA reductase, the enzyme that catalyses the early and rate-limiting step in chole ... Show more
Precaution
History of liver disease. Increased risk of rhabdomyolysis in severe infection, hypotension, major surgical trauma, uncontrolled seizures or severe me ... Show more
Side Effect
1-10%
CPK elevation (>3x ULN) (5%),Constipation (2%),Upper respiratory infection (9%),Flatulence (1-2%),Transaminases increased (>3x ULN) (1%),Headac ... Show more
Interaction
May increase bleeding risk w/ anticoagulants. Reduced serum levels w/ bosentan, efavirenz and rifampicin. Increased risk of myopathy and rhabdomyolysi ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.