Topmate 25 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consu...
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CONSULT YOUR DOCTOR
Topmate 25 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Topmate 25 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Topmate 25 should be used with caution in patients with kidney disease. Dose adjustment of Topmate 25 may be needed. Please consult your doctor.
CAUTION
Topmate 25 should be used with caution in patients with liver disease. Dose adjustment of Topmate 25 may be needed. Please consult your doctor.
Medicine Overview of Topmate 25mg Tablet
Introduction
Topmate 25 is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).
Topmate 25 controls seizures by de...
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Uses of Topmate 25
Epilepsy/Seizures
Prevention of migraine
Lennox–Gastaut syndrome
Side effects of Topmate 25
Common
Abdominal pain
Diarrhea
Dizziness
Fatigue
Fever
Loss of appetite
Memory impairment
Nausea
Nervousness
Numbness
Psychomotor impairment
Sleepiness
Speech disorder
Taste change
Upper respiratory tract infection
Visual impairment
Weight loss
How to use Topmate 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topmate 25 may be taken with or without food, but it is better to take it at a fixed time.
How Topmate 25 works
Topmate 25 is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
What if you forget to take Topmate 25?
If you miss a dose of Topmate 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Topmate 25. This can reduce the risk of kidney stones.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Oral
Partial-Onset or Primary Generalized Tonic-Clonic Seizures
Monotherapy
Adult: 25 mg PO q12hr initially; may increase by 50 mg/day at weekly in...
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Child Dose
Oral
Partial-Onset or Primary Generalized Tonic-Clonic Seizures
Monotherapy
<2 years: Safety and efficacy not established
2 to <10 years: 25 mg...
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Renal Dose
Renal impairment: Moderate to severe: Doses should be halved. Haemodialysis: supplemental dose equal to about ½ of the daily dose should be given in d...
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Contraindication
Contraindicated in persons showing hypersensitivity to any component of this preparation.
Mode of Action
Topiramate is a sulfamate-substituted monosaccharide with precise mechanism of action unknown. It may be due to various mechanisms e.g. blocking of vo...
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Precaution
Renal or hepatic impairment, pregnancy, lactation. May impair ability to drive or operate machinery. Maintain adequate hydration to reduce the risk o...
Coadmin with antiepileptic drugs e.g. phenytoin, carbamazepine, phenobarbital decreases plasma concentration of topiramate. Possible increase in pheny...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.