12-24 Hours
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Tresiba FlexTouch
Novo Nordisk
Generic: Insulin Degludec
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Tresiba FlexTouch.
CONSULT YOUR DOCTOR
Tresiba FlexTouch may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Tresiba FlexTouch is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
CAUTION
Tresiba FlexTouch should be used with caution in patients with kidney disease. Dose adjustment of Tresiba FlexTouch may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised.
CAUTION
Tresiba FlexTouch should be used with caution in patients with liver disease. Dose adjustment of Tresiba FlexTouch may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised.
Medicine Overview of Tresiba FlexTouch 100IU/ml Injection
Introduction
Tresiba FlexTouch is an ultra long-acting type of insulin used to treat types 1 and 2 diabetes mellitus in both adults and children. It provides a steady level of insulin in the body for an entire day and helps control blood sugar levels. This helps to prevent complications of diabetes. Tresiba FlexTouch can be prescribed by itself or along with a fast-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. You should use this medicine regularly as per the dose advised to get the most...
... Show moreUses of Tresiba FlexTouch
- Diabetes mellitus (Type 1 & Type 2)
Side effects of Tresiba FlexTouch
Common
- Hypoglycemia (low blood glucose level)
- Injection site allergic reaction
- Lipodystrophy (skin thickening or pits at the injection site)
How to use Tresiba FlexTouch
Your doctor or nurse will guide you how to use this medicine.
How Tresiba FlexTouch works
Tresiba FlexTouch is a long-acting insulin that provides consistent, all-day sugar control. It works like your body's natural insulin. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.
What if you forget to take Tresiba FlexTouch?
If you miss a dose of Tresiba FlexTouch take it as soon as you remember. Do not take two doses of Tresiba FlexTouch within 8 hours of each other.
Quick Tips
- This medicine is injected under the skin. It needs to be injected once daily, at the same time every day.
- Injection below the skin of the abdomen results in faster absorption than other injection sites.
- Injection sites must be rotated to prevent hard lumps from developing at one site.
- Do not use if the preparation is no longer clear and colorless or if it contains particles.
- Hypoglycemia (low blood sugar level) is a common side effect. Always carry some sugary food or fruit juice with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
- Opened vials/cartridge stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Brief Description
Indication
Diabetes Mellitus
Administration
Inject SC once daily at any time of day
Inject SC into the thigh, upper arm, or abdomen
Rotate injection sites within the same region from one injection to the next to reduce the risk of lipodystrophy
Do not administer IV, IM, or in an insulin infusion pump
Adult Dose
Adult: S/C: Insulin Degludec is ultra long-acting basal insulin for once-daily at any time of the day, preferably at the same time every day. Initiation: Patients with type 2 diabetes mellitus: The recommended daily starting dose is 10 units followed by individual dosage adjustments. Patients with type 1 diabetes mellitus: One third to one half of the total daily insulin dose; as a general rule, 0.2-0.4 units/kg can be used to calculate the initial total daily insulin dose in insulin-naïve patients with type 1 diabetes Insulin Degludec is to be used once-daily with meal-time insulin and requires subsequent individual dosage...
... Show moreChild Dose
Safety and efficacy not established
Contraindication
Hypersensitivity to the active substance or to any of the excipients.Hypoglycaemia, Hyperglycaemia, Eye disorder.
Mode of Action
Once-daily basal insulin analogue
Insulin and its analogues lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production; insulin inhibits lipolysis and proteolysis and enhances protein synthesis; targets include skeletal muscle, liver, and adipose tissue
Precaution
Insulin Degludecs must not be injected into a vein (intravenously) or a muscle (intramuscularly) and must not be used in infusion pumps.
There is no experience with Insulin Degludec in children and adolescents under 18 years of age.
Lactation: Unknown if distributed in human breast milk
Side Effect
>10%
Nasopharyngitis (12.9-23.9%),Severe hypoglycemic episode (0.3-12.3%),Upper respiratory tract infection (8.4-11.9%),Headache (8.8-11.8%)
1-10%
Diarrhea (6.3%),Sinusitis (5.1%),Gastroenteritis (5.1%),Injection site reactions (3.8%),Peripheral edema (0.9-3%)
<1%
Lipodystrophy
Interaction
Possible absence of hypoglycaemic warning symptoms with ?-blockers. Decreased hypoglycaemic effect with corticosteroids, danazol, diazoxide, diuretics, glucagon, isoniazid, phenothiazine derivatives, somatropin, sympathomimetic agents, thyroid hormones, oestrogens, progestins (e.g. in oral contraceptives), protease inhibitors and atypical antipsychotic (e.g. olanzapine and clozapine). Increased hypoglycaemic effect with oral antidiabetic agents, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, propoxyphene, salicylates and sulfonamide antibiotics. Decreased insulin resistance with octreotide and lanreotide. Increased risk of wt gain and peripheral oedema with pioglitazone, rosiglitazone. Decreased effect of sermorelin.
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