Consuming alcohol with Twicef does not cause any harmful side effects.
SAFE IF PRESCRIBED
Twicef is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Twicef is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Avoid prolonged use of Twicef, since it may have possible effects such as rash and diarrhea.
CONSULT YOUR DOCTOR
It is not known whether Twicef alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Twicef should be used with caution in patients with kidney disease. Dose adjustment of Twicef may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Twicef is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Twicef may not be needed in these patients. Please consult your doctor.
Medicine Overview of Twicef 500mg Capsule
Introduction
Twicef is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the throat, ears, urinary tract, skin, and soft tissues. It kills bacteria, which helps to improve your symptoms and cure the infection. Twicef may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full...
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Uses of Twicef
Bacterial infections
Side effects of Twicef
Common
Rash
Vomiting
Allergic reaction
Stomach pain
Nausea
Diarrhea
How to use Twicef
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Twicef may be taken with or without food, but it is better to take it at a fixed time.
How Twicef works
Twicef is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
Quick Tips
Your doctor has prescribed Twicef to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Take it with food to avoid an upset stomach.
Discontinue Twicef and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Avoid consuming alcohol while taking Twicef as it may cause increased side effects.
May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
Adult Dose
Oral
Tonsillitis; Skin and skin structure infections; Streptococcal pharyngitis; Urinary tract infections
Adult: 1-2 g daily as a single or in 2 divided doses.
Hepatic impairment: No dosage adjustment needed.
Child Dose
Oral
Tonsillitis; Skin and skin structure infections; Streptococcal pharyngitis; Urinary tract infections
Child: >6 yr <40 kg: 30-50 mg/kg daily as a single or in 2 divided doses, up to 100 mg/kg daily.
Renal Dose
Renal impairment:
CrCl (ml/min)
26-50 0.5-1 g bid.
11-25 0.5-1 g once daily.
<10 0.5-1 g every 36 hr.
Contraindication
Hypersensitivity to cephalosporins.
Mode of Action
Cefadroxil binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. Cefadroxil is not active against Proteus, Pseudomonas, Enterobacter, Morganella, Serratia and Listeria monocytogenes.
Precaution
Impaired renal function; pregnancy and lactation.
Lactation: enters breast milk; use with caution
Pregnancy Category: B
Lactation: enters breast milk; use with caution
Interaction
Concomitant use w/ bacteriostatic antibiotics (e.g. tetracycline, erythromycin, sulfonamides, chloramphenicol) may cause antagonistic effect. May potentiate nephrotoxic effects of aminoglycoside antibiotics, polymyxin B, colistin or high-dose loop diuretics. May enhance the anticoagulant effect of vit K antagonists. May diminish the therapeutic effect of BCG, typhoid vaccine and Na picosulfate. May attenuate the effect of oral contraceptives. Increased serum concentration w/ probenecid. Reduced bioavailability w/ colestyramine.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.