It is not known whether it is safe to consume alcohol with Tyronib. Please consult your doctor.
CONSULT YOUR DOCTOR
Tyronib is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Tyronib is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Lactating women should not breastfeed while using this drug and one month after stopping it.
UNSAFE
Tyronib may cause side effects which could affect your ability to drive.
CAUTION
Tyronib should be used with caution in patients with kidney disease. Dose adjustment of Tyronib may be needed. Please consult your doctor.
CAUTION
Tyronib should be used with caution in patients with severe liver disease. Dose adjustment of Tyronib may be needed. Please consult your doctor.
Medicine Overview of Tyronib 400mg Tablet
Introduction
Tyronib belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor.
Tyronib should be taken with fo ... Show more
Uses of Tyronib
Blood cancer (Chronic myeloid leukaemia)
Blood cancer (Acute lymphocytic leukemia)
Gastrointestinal stromal tumour
Side effects of Tyronib
Common
Abdominal pain
Diarrhea
Fatigue
Muscle cramp
Musculoskeletal (bone, muscle or joint) pain
Nausea
Rash
Vomiting
How to use Tyronib
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tyronib is to be taken with food.
How Tyronib works
Tyronib is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl posi ... Show more
What if you forget to take Tyronib?
If you miss a dose of Tyronib, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
Always take it with food and a full glass of water to prevent nausea.
It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
Water retention and swelling are very common side effects of Tyronib. Notify your doctor if you have unexpected rapid weight gain.
Do not change the dose or discontinue use without consulting your doctor.
Notify your doctor about all the medications you are taking, including over the counter medicines and dietary supplements.
Your doctor may get regular blood tests done to monitor your liver function and the number of blood cells in your blood.
Brief Description
Indication
Chronic myeloid leukaemia, Acute lymphoblastic leukaemia, Myelodysplastic disease, Hypereosinophilic syndrome, Mastocytosis, Dermatofibrosarcoma protu ... Show more
Administration
Should be taken with food and large glass of water.
Adult Dose
Acute Lymphoblastic Leukemia
Indicated for adults with relapsed or refractory Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (AL ... Show more
Child Dose
Chronic Myeloid Leukemia
Indicated for newly diagnosed adult and pediatric patients with Philadelphia chromosome positive (Ph+) chronic myeloid leuke ... Show more
Contraindication
Hypersensitivity. Lactation.
Mode of Action
Imatinib, is a tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase created by the Philadelphia chromosome abnormality in chronic myelo ... Show more
Precaution
Cardiac disease or increased risk for CHF. Monitor for signs of severe fluid retention. Monitor CBC regularly. Renal and hepatic impairment. Monitor L ... Show more
Side Effect
>10%
Edema (53%),Neutropenia (Grade 3: 7-27%; Grade 4: 3-48%),Nausea (43%),Muscle cramps (35%),Musculoskeletal pain (34%),Thrombocytopenia (Grade 3: ... Show more
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.