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Valsartil 40
Incepta Pharmaceuticals Ltd.
Generic: Valsartan
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Valsartil 40.
CONSULT YOUR DOCTOR
Valsartil 40 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Valsartil 40 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE
Valsartil 40 does not usually affect your ability to drive.
CAUTION
Valsartil 40 should be used with caution in patients with severe kidney disease. Dose adjustment of Valsartil 40 may be needed. Please consult your doctor.
Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
CAUTION
Valsartil 40 should be used with caution in patients with liver disease. Dose adjustment of Valsartil 40 may be needed. Please consult your doctor.
Medicine Overview of Valsartil 40mg Tablet
Introduction
Valsartil 40 is a medicine used to treat high blood pressure and heart disease. Lowering blood pressure helps to prevent future heart attack and stroke. This medicine is also effective in preserving kidney function in patients with diabetes. Valsartil 40 can be prescribed either alone or in combination with other medicines. It may be taken with or without food during the day or at night. However, try to take it at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or if your blood pressure is...
... Show moreUses of Valsartil 40
- Hypertension (high blood pressure)
- Heart failure
- Prevention of heart attack and stroke
Side effects of Valsartil 40
Common
- Headache
- Dizziness
- Flu-like symptoms
- Stomach pain
- Decreased blood pressure
- Diarrhea
- Back pain
- Rash
- Increased creatinine level in blood
How to use Valsartil 40
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valsartil 40 may be taken with or without food, but it is better to take it at a fixed time.
How Valsartil 40 works
Valsartil 40 is an angiotensin receptor blocker (ARB). It relaxes the blood vessel by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure, allowing the blood to flow more smoothly to different organs and the heart to pump more efficiently.
What if you forget to take Valsartil 40?
If you miss a dose of Valsartil 40, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- It can make you feel dizzy for the first few days. Rise slowly if you have been sitting or lying down for a long time.
- Your doctor may get regular tests done to monitor the level of urea, creatinine, and potassium in your blood.
- Avoid taking anti-inflammatory medicines such as ibuprofen along with this medicine without consulting your doctor.
- Do not take Valsartil 40 if you are pregnant or breastfeeding.
- Do not stop taking it suddenly without talking to your doctor.
Brief Description
Indication
Heart failure, Hypertension, Post myocardial infarction
Administration
May be taken with or without food.
Adult Dose
Oral
Hypertension
Adult: Initially, 80 mg once daily, may be increased to 160 mg once daily if needed. Max: 320 mg once daily.
Heart failure
Adult: Initially, 40 mg bid, may be increased to 160 mg bid if tolerated.
Post myocardial infarction
Adult: Start as early as 12 hr after MI in stable patients at an initial dose of 20 mg bid, doubled at intervals over a few wk up to 160 mg bid if tolerated.
Elderly: No dosage adjustment needed.
Hepatic impairment: Mild to moderate: Max: 80 mg once daily. Severe: Contraindicated.
Child Dose
Oral
Hypertension
Child: As tab: >6 yr 80 kg: Initially, 80 mg once daily. Max: 320 mg once daily.
Renal Dose
Renal impairment
CrCl >30 mL/min: No dose adjustment necessary in adults
CrCl <30 mL/min: Use with caution in adults; not studied in children
Contraindication
Hypersensitivity; severe hepatic impairment, cirrhosis or biliary obstruction; primary hyperaldosteronism. Pregnancy (2nd and 3rd trimesters) and lactation.
Mode of Action
Valsartan, an angiotensin II type 1 (AT1) receptor antagonist, produces its BP lowering effects by inhibiting angiotensin II-induced vasoconstriction, aldosterone release and renal reabsorption of Na.
Precaution
Patients w/ renal artery stenosis, heart failure, aortic or mitral stenosis, severe Na and/or volume depletion. Renal and mild to moderate hepatic impairment. Lactation. Monitoring Parameters Monitor BP, electrolytes, renal function. Monitor serum K levels every dose increment and periodically thereafter.
Side Effect
>10%
Dizziness (17%; heart failure),Increased blood urea nitrogen (BUN; 17%)
1-10%
Hyperkalemia (4-10%),Dizziness (2-8%; hypertension),Hypotension (1-7%; heart failure),Fatigue (3%),Viral infection (3%),Neutropenia (2%),Syncope (>1%),Upper abdominal pain (>1%),Vertigo (>1%)
Frequency Not Defined
Headache,Cough (rare)
Potentially Fatal: Blood dyscrasias (e.g. neutropenia).
Interaction
May antagonise hypotensive effects and increase the risk of renal impairment w/ NSAIDs. Increased risk of hyperkalaemia w/ K-sparing diuretics, K supplements or K-containing salt substitutes.
Potentially Fatal: Increased risk of hypotension, hyperkalemia and changes in renal function (including acute renal failure) when used w/ aliskiren in patients w/ diabetes and renal impairment (GFR <60 mL/min).
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