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Azelast
Incepta Pharmaceuticals Ltd.
Generic: Azelastine Hydrochloride
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Azelast may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Azelast is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
To reduce the amount of Azelast that reaches the breastmilk, remove the excess solution with an absorbent tissue.
Medicine Overview of Azelast 137mcg Nasal Spray
Introduction
Azelast belongs to a group of medicines called antihistamines. It is used to treat sneezing, runny or stuffy nose caused by allergies (allergic rhinitis). Follow your doctor's instructions precisely for using Azelast in the nose. It is used as a nasal spray, so never consume it orally. You should use it in the dose and duration as advised by your doctor. Before using it, inform your doctor if you have an infection, injury or ulceration in the inside of the nose. Since it is a nasal spray, it does not expose the rest of your body to the medicine and...
... Show moreUses of Azelast
- Sneezing and runny nose due to allergies
Side effects of Azelast
Common
- Taste change
How to use Azelast
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.
How Azelast works
Azelast is an antihistaminic medication. It treats allergy symptoms such as runny nose, sneezing, and itchy nose by blocking the effects of a chemical messenger (histamine) in the body.
What if you forget to take Azelast?
If you miss a dose of Azelast, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- The right way to use the nasal spray:
- Avoid deep breathing as it will cause medication to go back to the throat and make it less effective.
- Do not share the bottle with anyone else so that you do not spread germs.
- Azelast should be avoided in patients with recent nasal ulcers, nasal surgery, or nasal trauma.
Brief Description
Indication
Allergic rhinitis, vasomotor rhinitis.
Administration
Prime with 4 sprays before initial use; if idle for 3 days, reprime with 2 sprays
Adult Dose
Allergic Rhinitis:
Adults: 2 sprays per nostril twice daily.
Child Dose
Allergic Rhinitis: Children 5 years to 11 years of age: 1 spray into each nostril twice daily.
Children >12 years: 2 sprays per nostril twice daily.
Contraindication
Known hypersensitivity to Azelastine Hydrochloride or any of its components.
Mode of Action
Azelastine blocks histamine H1-receptor activity and inhibits release of inflammatory mediators from mast cells.
Precaution
In clinical trials, the occurrence of somnolence has been reported in some patients taking Azelastine Hydrochloride Nasal Spray; due caution should therefore be exercised when driving a car or operating potentially dangerous machinery. Concurrent use of Azelastine Hydrochloride Nasal Spray with Alcohol or other CNS depressants should be avoided because additional reductions in alertness and additional impairment of CNS performance may occur.
Lactation: Not known if excreted in breast milk; use caution
Side Effect
>10%
Bitter taste (8-19.7%),Headache (8-14.8%),Somnolence (1-11.5%),Cold symptoms/rhinitis (2-17%),Cough (11%)
1-10%
Nasal burning (4.1%),Sneezing (3.1%),Dry mouth (2.8%),Nausea (2.8%),Conjunctivitis (2-5%),Asthma (5%),Fatigue (2.3%),Rhinitis (2.3%),Pharyngitis (4%),Dizziness (2%),Weight increase (2%),Myalgia (<2%)
<1%
Amenorrhea,Breast pain,Constipation,Contact dermatitis,Eczema,Flushing,Glossitis,Hyperkinesia,Hypertension,Tachycardia,Vertigo,Vomiting
Pregnancy Category Note
Pregnancy Limited data from postmarketing experience over decades of use in pregnant women have not identified any drug associated risks of miscarriage, birth defects, or other adverse maternal or fetal outcomes Animal data In animal reproduction studies, there was no evidence of fetal harm at oral doses approximately 5 times the clinical daily dose; oral administration to pregnant mice, rats, and rabbits, during the period of organogenesis, produced developmental toxicity that included structural abnormalities, decreased embryo-fetal survival, and decreased fetal body weights at doses 270 times and higher than maximum recommended human daily intranasal dose of 1.096 mg; relevance of...
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