It is not known whether it is safe to consume alcohol with Xaloplat. Please consult your doctor.
CONSULT YOUR DOCTOR
Xaloplat is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Xaloplat is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
UNSAFE
Xaloplat may cause side effects which could affect your ability to drive.
Oxaliplatin_name$ treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.
CAUTION
Xaloplat should be used with caution in patients with severe kidney disease. Dose adjustment of Xaloplat may be needed. Please consult your doctor.
Limited information is available on the use of Xaloplat in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
CAUTION
Xaloplat should be used with caution in patients with liver disease. Dose adjustment of Xaloplat may be needed. Please consult your doctor.
Medicine Overview of Xaloplat 50mg/vial Infusion
Introduction
Xaloplat is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.
Xaloplat is given as an injection into vein by a qualified medical professional. Your doctor will decide w ... Show more
Uses of Xaloplat
Cancer of colon and rectum
Side effects of Xaloplat
Common
Nausea
Fatigue
Anemia (low number of red blood cells)
Vomiting
Diarrhea
Decreased white blood cell count (neutrophils)
Low blood platelets
Increased liver enzymes
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)
How to use Xaloplat
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Xaloplat works
Xaloplat is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
What if you forget to take Xaloplat?
If you miss a dose of Xaloplat, please consult your doctor.
Quick Tips
Xaloplat is given as an injection into veins under the supervision of a doctor.
Brief Description
Indication
Colorectal cancer, Colon cancer
Administration
IV Preparation
Reconstitute by adding 10 mL (for 50 mg vial) or 20 mL (for 100 mg vial) of SWI or D5W. Dilute required amount of reconstituted soluti ... Show more
Adult Dose
Intravenous
Advanced colorectal cancer
Adult:
Day 1: Oxaliplatin 85 mg/m² IV + leucovorin 200 mg/m² IV infused over 2 hr, THEN
5-FU 400 mg/m² IV ... Show more
Child Dose
Safety and efficacy not established
Renal Dose
Renal Impairment
Exposure of unbound platinum tends to increase in renally impaired patients
Mild (CrCl 50-80 mL/min): No dosage adjustment required ... Show more
Contraindication
Pregnancy. Peripheral neuropathy with functional impairment. Severe renal impairment.
Mode of Action
Oxaliplatin, a platinum-containing complex similar to cisplatin, is an alkylating agent. After intracellular hydrolysis, the platinum compound binds t ... Show more
Precaution
Should be administered under the supervision of an experienced cancer chemotherapy physician. Use appropriate precautions for handling and disposal. M ... Show more
Side Effect
>10%
Peripheral neuropathy (76%),Anemia (64%),Nausea (64%),Fatigue (61%),Diarrhea (46%),Vomiting (37%),Abdominal pain (31%),Constipation (31%),Thromb ... Show more
Interaction
May decrease plasma levels of digoxin. May increase risk of toxicity with nephrotoxic drugs. When administered as sequential infusions, taxane derivat ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.