Xelpac is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Xelpac is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
UNSAFE
Xelpac may cause side effects which could affect your ability to drive.
As there is no reason why you cannot continue driving between courses of Xelpac but you should remember that this medicine contains some alcohol and it may be unwise to drive
SAFE IF PRESCRIBED
Xelpac is safe to use in patients with kidney disease. No dose adjustment of Xelpac is recommended.
However, talk to your doctor if you have any underlying kidney disease.
CAUTION
Xelpac should be used with caution in patients with liver disease. Dose adjustment of Xelpac may be needed. Please consult your doctor.
Use of Xelpac is not recommended in patients with severe liver disease.
Medicine Overview of Xelpac 300mg/vial Injection
Introduction
Xelpac is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how of ... Show more
Uses of Xelpac
Breast cancer
Non-small cell lung cancer
Pancreatic cancer
Side effects of Xelpac
Common
Nausea
Vomiting
Weakness
Low blood platelets
Rash
Upper respiratory tract infection
Urinary tract infection
Bleeding
Anemia (low number of red blood cells)
Flushing (sense of warmth in the face, ears, neck and trunk)
Hair loss
Decreased blood pressure
Peripheral neuropathy (tingling and numbness of feet and hand)
Diarrhea
Decreased white blood cell count (neutrophils)
How to use Xelpac
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Xelpac works
Xelpac is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.
Quick Tips
Xelpac is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.
Do not take Xelpac if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medici ... Show more
Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of inf ... Show more
Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.
Brief Description
Indication
Ovarian carcinoma, Breast cancer, Lung cancer, Kaposi's sarcoma
Administration
Reconstitution: Paclitaxel must be diluted before infusion. It can be diluted in 0.9% sodium chloride inj, 5% dextrose inj, 5% dextrose and 0.9% sodiu ... Show more
Adult Dose
Intravenous
Ovarian carcinoma
Adult: Primary treatment (in combination with cisplatin or carboplatin): 135 mg/m2 infused over 24 hr followed by cisp ... Show more
Child Dose
Safety and efficacy not established
Contraindication
History of hypersensitivity (especially macrogol glycerol ricinolate). Patients with baseline neutropenia of <1500 cells/mm3 (<1000 cells/mm3 for kapo ... Show more
Mode of Action
Paclitaxel promotes microtubule formation by enhancing the action of tubulin dimers, stabilising existing microtubules and preventing their disassembl ... Show more
Precaution
Bone marrow suppression during therapy. Monitor cardiac function if conduction abnormalities result. Premedicaton (with corticosteroid, antihistamine ... Show more
Side Effect
>10%
Neutropenia (78-100%),Alopecia (55-96%),Anemia (47-96%),Arthralgia/myalgia (93%),Diarrhea (90%),Leukopenia (90%),Nausea/vomiting (9-88%),Opportu ... Show more
Interaction
Myelosuppression was more profound when given after cisplatin than with the alternate sequence (e.g., paclitaxel before cisplatin). CYP2C8 inducers e. ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.