Inopil PLUS may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Inopil PLUS is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Inopil PLUS is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Inopil PLUS may cause side effects which could affect your ability to drive.
Inopil PLUS usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability.
CAUTION
Inopil PLUS should be used with caution in patients with kidney disease. Dose adjustment of Inopil PLUS may be needed. Please consult your doctor.
Caution should be advised in patients with renal impairment.
CAUTION
Inopil PLUS should be used with caution in patients with liver disease. Dose adjustment of Inopil PLUS may be needed. Please consult your doctor.
Medicine Overview of Inopil PLUS 1.25mg+4mg Tablet
Introduction
Inopil PLUS is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce the chances of any future heart attack and stroke. Inopil PLUS should be taken on empty stomach, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it,...
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Uses of Inopil PLUS
Hypertension (high blood pressure)
Side effects of Inopil PLUS
Common
Nausea
Diarrhea
Stomach pain
Constipation
Vomiting
Headache
Vertigo
Dizziness
Altered vision
Numbness
Ringing in ear
Breathlessness
Indigestion
Allergic reaction
Skin rash
Itching
Cramps
Fatigue
How to use Inopil PLUS
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Inopil PLUS is to be taken empty stomach.
How Inopil PLUS works
Inopil PLUS is a combination of two medicines: Perindopril and indapamide which lower blood pressure effectively. Perindopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently. Indapamide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
Quick Tips
You have been prescribed Inopil PLUS for the treatment of high blood pressure.
It also lowers your risk of stroke and heart attack.
Take it in the morning with breakfast, to avoid getting up at night to urinate.
Inopil PLUS may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Inform you doctor about any cough, or throat irritation that doesn't go away.
Inopil PLUS may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.
Do not take Inopil PLUS if you’re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.
Brief Description
Indication
Hypertension
Adult Dose
Oral
Hypertension
Adult: 1 tab once daily in the morning.
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
<30 Avoid use.
30-60 Dose adjustment may be needed
Contraindication
Hypersensitivity. Severe renal impairment (CrCl <30 ml/min), hypokalaemia, severe hepatic impairment or hepatic encephalopathy, history of angioedema associated with treatment with an ACE inhibitor, children. Dialysis patients or patients with untreated decompensated heart failure. Hereditary/idiopathic angioneurotic oedema. Pregnancy and lactation.
Mode of Action
Perindopril is an ACE inhibitor, which acts by inhibiting the conversion of angiotensin I to angiotensin II, reducing the activity of the sympathetic nervous system and inhibiting enzyme kininase, which is involved in the conversion of bradykinin and other substances. Indapamide is a sulfonamide derivative with an indole ring. It inhibits the reabsorption of sodium in the cortical dilution segment, thus increasing urinary output, resulting in an antihypertensive effect.
Precaution
Impaired renal function, risk of hypotension and electrolyte imbalance. Regular monitoring of renal function and plasma levels of potassium are recommended. Blood glucose levels should be monitored in diabetic patients especially in those with low serum potassium levels. Increased risk of neutropenia/agranulocytosis in immunosuppressed patients. Treatment should be discontinued immediately if there is angioneurotic oedema of the face, extremities, lips, tongue, glottis and/or larynx.
Side Effect
Dry cough, headache, bradycardia, dizziness, asthenia, hypokalaemia and orthostatic hypotension. GI effects such as constipation, dry mouth, nausea, epigastric pain, anorexia, abdominal pain and taste disturbance.
Interaction
Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin.
Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.
ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.