Promargan may cause excessive drowsiness with alcohol.

Promargan may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Promargan is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. For prolonged use and repeated doses of Promargan, observe the baby for excessive sleepiness.

Promargan may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Promargan is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Promargan may not be needed in these patients. Please consult your doctor. However, caution is advised in patients with severe kidney disease as it may cause excessive sleepiness in them.

Promargan should be used with caution in patients with liver disease. Dose adjustment of Promargan may be needed. Please consult your doctor.