Lok 50 Plus is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Lok 50 Plus is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Lok 50 Plus may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Lok 50 Plus should be used with caution in patients with severe kidney disease. Dose adjustment of Lok 50 Plus may be needed. Please consult your doctor.
Use of Lok 50 Plus is not recommended in patients with severe kidney disease.
CAUTION
Lok 50 Plus should be used with caution in patients with liver disease. Dose adjustment of Lok 50 Plus may be needed. Please consult your doctor.
Medicine Overview of Lok 50 Plus 12.5mg+50mg Tablet
Introduction
Lok 50 Plus is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.
You can take Lok 50 Plus with or without food. ... Show more
Uses of Lok 50 Plus
Hypertension (high blood pressure)
Side effects of Lok 50 Plus
Common
Nausea
Taste change
Upset stomach
Diarrhea
Headache
Dizziness
Weakness
Decreased blood pressure
Increased blood uric acid
Increased blood lipid level
Glucose intolerance
Electrolyte imbalance
How to use Lok 50 Plus
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lok 50 Plus may be taken with or without food, but it is better to take it at a fixed time.
How Lok 50 Plus works
Lok 50 Plus is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vesse ... Show more
Quick Tips
You have been prescribed Lok 50 Plus for the treatment of high blood pressure.
It can be taken with or without food.
Lok 50 Plus may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle wea ... Show more
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Use of Lok 50 Plus during pregnancy or breastfeeding is unsafe.
It may also decrease the risk of stroke and heart attacks.
Brief Description
Indication
Hypertension, Stroke, risk reduction of hypertensive or LVH patients
Adult Dose
Hypertension
Initial: 50 mg/12.5 mg PO qDay
If dose titrated upward, do not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO ... Show more
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment
CrCl <30 mL/min: Do not use thiazide-containing products; loop diuretic preferred
CrCl >30 mL/min: No dosage adjustment required
Hydrochlorothiazide increases renal excretion of sodium and chloride and reduces cardiac load. Losartan is an angiotensin II receptor (type AT1) antag ... Show more
Precaution
Existing electrolyte disturbances; hepatic cirrhosis; severe hepatic failure; oedema; elderly (>75 yr); renal impairment; hepatic impairment; diabetes ... Show more
Side Effect
>10%
Losartan
Fatigue (14%),Hypoglycemia (14%),Chest pain (12%),Cough, incidence higher in previous cough related to ACE therapy (3-11%)
1-10%
L ... Show more
Interaction
Reduced excretion of lithium; effect of diuretic, natriuretic & other antihypertensive w/ NSAIDs including selective COX-2 inhibitors. Do not co-admin ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.