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Open 500
Opsonin Pharma Limited
Generic: Phenoxymethyl Penicillin
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Open 500 does not cause any harmful side effects.
SAFE IF PRESCRIBED
Open 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Open 500 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
SAFE
Open 500 does not usually affect your ability to drive.
CAUTION
Open 500 should be used with caution in patients with kidney disease. Dose adjustment of Open 500 may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Open 500 in patients with liver disease. Please consult your doctor.
Medicine Overview of Open 500mg Tablet
Introduction
Open 500 is an antibiotic used to treat a variety of bacterial infections, like, infections of the throat, ear, nasal sinuses, respiratory tract, skin and soft tissues. It is also used in the treatment of sexually transmitted diseases such as syphilis. Open 500 is also used to prevent some infections such as Rheumatic fever and infection of the heart valves (bacterial endocarditis) in people with pre-existing heart disease. It is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. This tablet should be swallowed empty stomach with a glass of water. It...
... Show moreUses of Open 500
- Bacterial infections
- Syphilis
Side effects of Open 500
Common
- Rash
- Vomiting
- Allergic reaction
- Nausea
- Diarrhea
How to use Open 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Open 500 is to be taken empty stomach.
How Open 500 works
Open 500 is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
Quick Tips
- You have been prescribed Open 500 for the treatment of bacterial infections.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Brief Description
Indication
Tonsillitis, Pharyngitis, Skin & soft tissue infections, Anthrax, Lyme disease, Rheumatic fever, Spleen disorders, Dental Abscesses, gingivitis, upper respiratory tract, scarlet fever, erysipelas, otitis media, Vincent's infection
Adult Dose
Oral
Adult:
Usually 250-500 mg 6 hourly
Prophylaxis of recurrent rheumatic fever
250 mg twice daily.
Streptococcal infections of the upper respiratory tract, including scarlet fever and erysipelas
125-250 mg 6-8 hrly for 10 days.
Pneumococcal infections of the respiratory tract, including otitis media
250-500 mg 6 hrly until patient is afebrile for at least 2 days.
Fusospirochetosis (Vincent's infection) of the oropharynx; Staphylococcal infections of the skin and soft tissue
250-500 mg 6-8 hrly.
Child Dose
Oral
Tablet
Children: PO 25–50 mg/kg/day q6h
Syrup
Dry Syrup: 1-2 tea-spoonful (5-10ml) 6 hourly
Forte Syrup: ½-1 tea-spoonful (2.5-5ml) 6 hourly
Infants: 62.5-125 mg 6 hourly
Contraindication
Hypersensitivity to penicillins.
Mode of Action
Inhibits the biosynthesis of cell wall mucopeptide; bactericidal against sensitive organisms when adequate concentrations are reached, and most effective during the stage of active multiplication; inadequate concentrations may produce only bacteriostatic effects.
Precaution
Monitor renal and haematologic systems periodically during prolonged therapy or if high dose is used. Use may result in overgrowth of nonsusceptible organisms. Cross-sensitivity with cephalosporins may occur. History of significant allergies and/or asthma. Pregnancy and lactation.
Side Effect
Nausea, vomiting, epigastric distress, diarrhoea, black hairy tongue; skin eruptions (maculopapular to exfoliative dermatitis), urticaria and other serum-sickness like reactions, laryngeal oedema; fever, eosinophilia.
Potentially Fatal: Anaphylaxis.
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