Caution is advised when consuming alcohol with Abixa 10. Please consult your doctor.
SAFE IF PRESCRIBED
Abixa 10 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CONSULT YOUR DOCTOR
Information regarding the use of Abixa 10 during breastfeeding is not available. Please consult your doctor.
UNSAFE
Abixa 10 may cause side effects which could affect your ability to drive.
CAUTION
Abixa 10 should be used with caution in patients with severe kidney disease. Dose adjustment of Abixa 10 may be needed. Please consult your doctor.
CAUTION
Abixa 10 should be used with caution in patients with severe liver disease. Dose adjustment of Abixa 10 may be needed. Please consult your doctor.
Limited information is available on the use of Abixa 10 in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Medicine Overview of Abixa 10mg Tablet
Introduction
Abixa 10 is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transm ... Show more
Uses of Abixa 10
Alzheimer's disease
Side effects of Abixa 10
Common
Dizziness
Headache
Confusion
Sleepiness
Diarrhea
Abnormal liver function tests
Balance disorder (loss of balance)
Breathlessness
Pulmonary hypertension (high blood pressure)
Hypersensitivity
How to use Abixa 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abixa 10 may be taken with or without food, but it is better to take it at a fixed time.
How Abixa 10 works
Abixa 10 is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Abixa 10 works by preventing the act ... Show more
What if you forget to take Abixa 10?
If you miss a dose of Abixa 10, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
You have been prescribed Abixa 10 to slow down the progression of Alzheimer's disease.
It is well tolerated and has lesser side effects as compared to other similar medicines.
Be cautious while driving or doing anything that requires concentration until you know how Abixa 10 affects you.
Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Brief Description
Indication
Alzheimer's dementia.
Administration
May be taken with or without food.
Adult Dose
Oral
Moderate to severe dementia in Alzheimer's disease
Adult: As hydrochloride: Initially, 5 mg daily in the morning for the 1st wk; increase dose ... Show more
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
5-29 Max: 10 mg daily.
30-49 10 mg daily (after initial dose of 5 mg daily), if well tolerate ... Show more
Contraindication
Hypersensitivity to memantine or components of the formulation. Severe renal impairment.
Mode of Action
Memantine, a derivative of amantadine, is a noncompetitive N-methyl-D-aspartate (NMDA)-receptor antagonist. It affects transmission of glutamate, the ... Show more
Precaution
Renal impairment; epilepsy. Pregnancy and lactation. Closely monitor patients with recent MI, uncompensated CHF, uncontrolled hypertension. Predisposi ... Show more
Side Effect
1-10%
Dizziness (7%),Confusion (6%),Headache (6%),Constipation (5%),Cough (4%),Hypertension (4%),Backache (3%),Pain (3%),Somnolence (3%),Syncope (3%) ... Show more
Interaction
May increase effects of antimuscarinics and dopaminergics. May reduce effects of antipsychotics and barbiturates. May alter effects of dantrolene, bac ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.