Docexan is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Docexan is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
CONSULT YOUR DOCTOR
It is not known whether Docexan alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
SAFE IF PRESCRIBED
Docexan is safe to use in patients with kidney disease. No dose adjustment of Docexan is recommended.
CAUTION
Docexan should be used with caution in patients with liver disease. Dose adjustment of Docexan may be needed. Please consult your doctor.
Medicine Overview of Docexan 80mg/2ml Injection
Introduction
Docexan is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.
It is given as an injection by a qualified medical professional. Your doctor will decide what dos ... Show more
Uses of Docexan
Breast cancer
Non-small cell lung cancer
Prostate cancer
Cancer of head and neck
Side effects of Docexan
Common
Breathlessness
Constipation
Edema (swelling)
Infection
Loss of appetite
Muscle pain
Nail disorder
Pain
Weakness
How to use Docexan
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Docexan works
Docexan is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.
Quick Tips
Docexan is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of hea ... Show more
Do not take Docexan if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medic ... Show more
Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
It may cause side effects such as swelling of hands, lips, and weight gain. To reduce these side effects your doctor may suggest some medica ... Show more
Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of inf ... Show more
Brief Description
Indication
Breast cancer, Lung cancer, Prostate cancer, Stomach cancer, Head/neck cancer
Administration
IV Preparation
Dual vial formulation
Requires 2-step dilution
Reconstitute vial contents (20 mg/0.5 mL or 80 mg/2 mL) with supplied diluent (13% (w ... Show more
Adult Dose
Intravenous
Breast cancer
Adult: 60-100 mg/m2 by infusion over 1 hr once every 3 wk. In combination w/ doxorubicin or capecitabine or as adjuvant th ... Show more
Renal Dose
Renal Impairment
Dose adjustment not necessary
Contraindication
Previous severe hypersensitivity reaction to docetaxel, the solvent or polysorbate 80. Severe neutropenia; pregnancy, severe liver impairment.
Mode of Action
Docetaxel disrupts the microtubular network in cells that is essential for vital mitotic and interphase cellular functions. It binds to the free tubul ... Show more
Precaution
Lactation. Hepatic impairment. Monitor liver blood function and blood counts regularly. Premedication with oral dexamethsaone at 16 mg daily for 3 day ... Show more
Side Effect
>50%
Alopecia,Anemia,Leukopenia,Neutropenia,Asthenia
10-50%
Fever,Infections,Fluid retention,Hypersensitivity,Skin reactions,Diarrhea,Nausea,Vomi ... Show more
Pregnancy Category Note
Pregnancy
Based on findings in animal reproduction studies and its mechanism of action, therapy can cause fetal harm when administered to a pregnant ... Show more
Interaction
CYP3A4 inducers, inhibitors, or substrates may alter docetaxel metabolism.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.