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Lotenate Plus

Eye Drop - (0.5%+0.3%)
arogga-brand
Pacific Pharmaceuticals Ltd.
Generic: Loteprednol Etabonate 0.5% + Tobramycin 0.3% Eye prep
180.00
৳ 200
10% OFF
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Lotenate Plus is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Lotenate Plus is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. To reduce the amount of Lotenate Plus that reaches the breastmilk, place pressure over the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.
UNSAFE
Lotenate Plus may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.

Medicine Overview of Lotenate Plus 0.5%+0.3% Eye Drop

Introduction
Lotenate Plus is a prescription medicine having a combination of medicines that is used to treat eye infections with inflammation. It stops the growth of bacteria and helps in relieving redness, itching and swelling. Lotenate Plus is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection...
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Uses of Lotenate Plus
  • Eye infection with inflammation
Side effects of Lotenate Plus
Common
  • Eye irritation
  • Eye discomfort
How to use Lotenate Plus
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Lotenate Plus works
Lotenate Plus is a combination of two medicines: Loteprednol etabonate and Tobramycin. Loteprednol etabonate is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy. Tobramycin is an antibiotic. It stops bacterial growth in the eye by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.
Quick Tips
  • Lotenate Plus is used for the treatment of bacterial skin infections.
  • It should be applied to the affected areas as a thin film, two or three times daily, or as advised by your doctor.
  • Do not use it more often or for longer than advised by your doctor.
  • Do not apply it to broken skin and avoid getting it in your eyes, nose or mouth.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • It may cause temporary burning, itching or a redness at application site. This is usually mild. Consult your doctor if you experience a more severe reaction.
  • Inform your doctor if your skin problem hasn't improved after seven days of treatment.
Brief Description
Indication
Keratitis, Allergic conjunctivitis, Iritis, Ocular inflammation, Bacterial ocular infection, Cyclitis
Adult Dose
Ocular Inflammation Indicated for steroid-responsive ocular inflammations with risk of superficial bacterial infections Adult: Instill 1 or 2 drops of into the conjunctival sac of the affected eye(s) every 4 to 6 hours.; may use as frequently as q1-2hr during first 24-48 hr Decrease frequency of administration as signs and symptoms improve
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Child Dose
Safety & efficacy not been established.
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Contraindication
Hypersensitivity to any component of the formulation or to other corticosteroids Viral, mycobacterial & fungal eye infections
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Mode of Action
Loteprednol is a synthetic nonfluorinated glucocorticoid. It stimulates the production of lipicortins, proteins that modulate the activity of prostaglandins and leukotrienes. Tobramycin acts by binding to 30S ribosomal subunits thus interfering with bacterial protein synthesis. It is active against many aerobic gram-negative bacteria and some aerobic gram-positive bacteria but inactive against Chlamydia, fungi, viruses, and most anaerobic bacteria.
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Precaution
History of herpes simplex infections May exacerbate infections by nonsusceptible organisms Monitor IOP if used >10 d Bacterial keratitis reported from inadvertent contamination of multiple dose ophthalmic solution Immunosuppression resulting from prolonged use of steroid use may result in secondary bacterial and fungal infections; steroids may also mask symptoms of infections and enhance existing ocular infections Ocular hypertension and/or glaucoma reported with prolonged corticosteroid use Discontinue use if sensitivity reaction to tobramycin develops Corticosteroid use following cataract surgery may delay healing Lactation: Excretion in milk unknown; use caution
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Side Effect
Prolonged use may increase: IOP, which may be associated with possible development of glaucoma and infrequent optic nerve damage; posterior sub-capsular cataract formation and perforation of the globe where there is thinning of the cornea or sclera. The most frequent adverse reactions to topical tobramycin are hypersensitivity and localized ocular toxicity, including lid itching and swelling and conjunctival erythema.
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Interaction
Enhanced neurotoxic and nephrotoxic effects w/ other aminoglycosides (e.g. amikacin, streptomycin), cefaloridine, viomycin, polymyxin B, colistin, cisplatin and vancomycin. Enhanced toxicity w/ potent diuretics (e.g. ethacrynic acid, furosemide). Prolonged secondary apnoea may occur when given to anaesthetised patients receiving neuromuscular blocking agents (e.g. succinylcholine, tubocurarine, decamethonium). Increased risk of nephrotoxicity w/ ciclosporin and other antibacterials (e.g. cephalosporins). Antagonistic effect w/ neostigmine and pyridostigmine. May potentiate the effect of warfarin and phenindione.
Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.