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UNSAFE
It is unsafe to consume alcohol with Flomyst-F 10/250 HFA.
CONSULT YOUR DOCTOR
Flomyst-F 10/250 HFA may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Flomyst-F 10/250 HFA is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medicine Overview of Flomyst-F 10/250 HFA 250mcg+10mcg/Puff Inhaler
Introduction
Flomyst-F 10/250 HFA is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It relaxes the muscles of the air passages and making it easier to breathe. Your doctor will tell you how often you need to use your inhaler. It's important that you take the lowest dose needed to effectively control your asthma. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must...
... Show moreUses of Flomyst-F 10/250 HFA
- Asthma
- Chronic obstructive pulmonary disease (COPD)
Side effects of Flomyst-F 10/250 HFA
Common
- Nausea
- Vomiting
- Respiratory tract infection
- Fungal infection of mouth
- Sore throat
- Headache
- Hoarseness of voice
- Cough
- Musculoskeletal (bone, muscle or joint) pain
- Increased heart rate
How to use Flomyst-F 10/250 HFA
Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.
How Flomyst-F 10/250 HFA works
Flomyst-F 10/250 HFA is a combination of two medicines: Formoterol and Fluticasone Propionate. Formoterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.
Quick Tips
- Flomyst-F 10/250 HFA is a combination of two medicines that opens the airways and makes it easier to breathe.
- This medicine is for inhalation only. The tablet should not be swallowed.
- It should be taken at the same time each day.
- It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
- Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
- Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Flomyst-F 10/250 HFA can lower blood potassium level.
- Only miniscule amounts of Flomyst-F 10/250 HFA may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Brief Description
Indication
Fluticasone and Formoterol is a fixed-dose combination metered-dose inhaler indicated for the regular treatment of, Asthma, where a long-acting ß2 agonist (LABA) in combination with an inhaled corticosteroid is appropriate.
Administration
Priming the inhaler Before using the inhaler for the first time, or if the inhaler has not been used for 3 days or more, or after exposure to freezing or refrigerated conditions (see section 6.4) the inhaler must be primed before use: • Remove the mouthpiece cover and shake the inhaler well. • Actuate (puff) the inhaler whilst pointing it away from the face. This step must be performed 4 times. • The inhaler should always be shaken immediately before use. Whenever possible patients should stand or sit in an upright position when inhaling from the inhaler. Steps to follow...
... Show moreAdult Dose
Inhalation
Per actuation Fluticasone + Formoterol: 50/5, 125/5 and 250/10 mcg
Recommended dose for Adults
250/10 mcg Inhaler: 2 inhalations (puffs) twice daily.
50 /5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening.
125/5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening.
... Show moreChild Dose
Child < 12years not recommended.
Recommended dose Adolescents aged 12 years and above:
50 /5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening.
125/5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening.
... Show moreContraindication
Hypersensitivity to the active substances or to any of the excipients.
.
... Show moreMode of Action
Fluticasone propionate is a synthetic, trifluorinated glucocorticoid with potent anti-inflammatory activity in the lungs when given by inhalation. Fluticasone propionate reduces symptoms and exacerbations of asthma with less adverse effects than when corticosteroids are administered systemically.
Formoterol fumarate is a long-acting selective β2 adrenergic receptor agonist. Inhaled formoterol fumarate acts locally in the lung as a bronchodilator. The onset of bronchodilating effect is rapid, within 1 - 3 minutes, and the duration of effect is at least 12 hours after a single dose.
... Show morePrecaution
Fluticasone + Formoterol inhaler should not be used to treat acute asthma symptoms for which a fast- and short-acting bronchodilator is required. Patients should be advised to have the medicine to be used for relief in an acute asthma attack available at all times. The prophylactic use of this inhaler in exercise-induced asthma has not been studied. For such use, a separate rapid-acting bronchodilator should be considered. Patients should not be initiated on Fluticasone + Formoterol inhaler during an exacerbation, or if they have significantly worsening or acutely deteriorating asthma. Serious asthma-related adverse events and exacerbations may occur during treatment...
... Show moreSide Effect
Hyperglycemia; headache, tremor, dizziness, dysgeusia; palpitations, ventricular extrasystoles; asthma exacerbation, dysphonia, throat irritation; dry mouth, peripheral oedema.
Interaction
Long-term treatment & co-administration w/ CYP3A4 inhibitors (eg, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nelfinavir, saquinavir, ketoconazole, telithromycin). Non-K sparing diuretics (loop or thiazide diuretics), xanthine derivatives, glucocorticosteroids. L-dopa, L-thyroxine, oxytocin, alcohol can impair cardiac tolerance towards β2-sympathomimetics. Concomitant use w/ MAOIs, furazolidone & procarbazine may precipitate hypertensive reactions. Concomitant use w/ anaesth & halogenated hydrocarbons can elevate risk of arrhythmias. Additive effects w/ β-adrenergics. Increase risk of arrhythmias w/ digitalis glycosides. Administer w/ extreme caution to patients concomitantly taking TCAs or MAOIs & during the immediate 2 wk period following discontinuation. Increased risk of ventricular arrhythmias w/ phenothiazines, quinidine, disopyramide,...
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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.