Consuming alcohol while taking Pactorin may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
SAFE IF PRESCRIBED
Pactorin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Pactorin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Pactorin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Pactorin is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pactorin may not be needed in these patients. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Pactorin in patients with liver disease. Please consult your doctor.
Medicine Overview of Pactorin 400mcg Spray
Introduction
Pactorin is used to treat and prevent heart-related chest pain (angina). Angina occurs when the heart muscle is not getting enough blood. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart.
Pactorin...
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Uses of Pactorin
Angina (heart-related chest pain)
Side effects of Pactorin
Common
Blurred vision
Decreased blood pressure
Dizziness
Headache
Increased heart rate
Lightheadedness
Paresthesia (tingling or pricking sensation)
How to use Pactorin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pactorin may be taken with or without food, but it is better to take it at a fixed time.
How Pactorin works
Pactorin is a nitrate. It works by relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain).
What if you forget to take Pactorin?
If you miss a dose of Pactorin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Pactorin may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Pactorin as it may cause increased dizziness.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
You may develop tolerance to Pactorin with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing sc...
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Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Pactorin as it may cause ...
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Brief Description
Indication
Angina pectoris, Acute myocardial infarction, Severe hypertension, Pulmonary edema.
Adult Dose
Oral
Stable angina
Adult: As SR tab/cap: 2.6-6.4 mg 3-4 times daily, adjust according to response. Max: 26 mg 4 times daily.
Sublingual Tablet
A...
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Renal Dose
Renal Failure
CrCl: 10-50 mL/min: Administer q24-72hr
CrCl: <10 mL/min: Administer q72-96hr
Contraindication
Hypersensitivity. Severe hypotension, heart failure, marked anaemia, hypertrophic obstructive cardiomyopathy, cerebral haemorrhage or head trauma, low...
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Mode of Action
Glyceryl trinitrate acts on the enzyme nitric oxide stimulating guanylate cyclase in the vascular smooth muscle cells resulting in the relaxation of s...
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Precaution
Severe hepatic or renal impairment, hypothyroidism, malnutrition, hypothermia. Cerebrovascular disease, lung disease or cor pulmonale. Pregnancy, lact...
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Side Effect
Common
Headache,Hypotension,Tachycardia,Dizziness,Lightheadedness,Blurred vision,Flushing,N/V,Nervousness,Xerostomia
Serious
Methemoglobinemia (r...
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Interaction
Enhances bioavailability of dihydroergotamine. Glyceryl trinitrate infusion may prolong pancuronium-induced neuromuscular blockade. May reduce the eff...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.