Coxib is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Coxib is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Coxib may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Coxib should be used with caution in patients with kidney disease. Dose adjustment of Coxib may be needed. Please consult your doctor.
Use of Coxib is not recommended in patients with severe kidney disease.
CAUTION
Coxib should be used with caution in patients with liver disease. Dose adjustment of Coxib may be needed. Please consult your doctor.
Use of Coxib is not recommended in patients with severe liver disease. Inform your doctor and stop taking this medicine if you develop any signs of liver toxicity.
Medicine Overview of Coxib 100mg Capsule
Introduction
Coxib is a pain relieving medicine. It alleviates pain, redness, and swelling in conditions such as osteoarthritis, rheumatoid arthritis, and pain during menstruation.
Coxib can be taken with or without food. You should take it regularly as advised ...
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Uses of Coxib
Pain relief
Osteoarthritis
Rheumatoid arthritis
Pain during menstruation
Side effects of Coxib
Common
Stomach pain
Diarrhea
Flatulence
Flu-like symptoms
Peripheral edema
How to use Coxib
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Coxib may be taken with or without food, but it is better to take it at a fixed time.
How Coxib works
Coxib is a non-steroidal anti-inflammatory drug (NSAID) called COX-2 inhibitors. It works by blocking the release of certain chemical messengers that are responsible for pain and inflammation (redness and swelling).
Quick Tips
Coxib helps relieve pain and inflammation.
It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen.
It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness.
Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
Do not take Coxib if you are pregnant, planning to conceive, or breastfeeding.
May be taken with or without food. Dose for OA/RA may be given w/ or w/o meals, but doses for FAP must be given w/ meals.
Adult Dose
Oral
Osteoarthritis
Adult: 200 mg/day as a single dose or in 2 divided doses. May increase to 200 mg bid, if necessary.
Rheumatoid arthritis
Adu...
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Child Dose
Juvenile idiopathic arthritis
Child: >2 yr >10 kg to <25 kg: 50 mg bid;
>25 kg: 100 mg bid.
Contraindication
Hypersensitivity including those in whom attacks of angioedema, rhinitis and urticaria have been precipitated by aspirin, NSAIDs or sulfonamides. Seve...
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Mode of Action
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor primarily responsible to reduce mediators of pain and inflammation. Its action is due to i...
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Precaution
History of GI bleeding; renal/hepatic insufficiency; asthma or allergic disorders; hypertension; monitor Hb or haematocrit levels for signs of anaemia...
Pregnancy category: C; D at >30 weeks' gestation (may cause premature closure of ductus arteriosus)
Lactation: Drug enters breast milk; use caution
Interaction
May increase plasma level w/ CYP2C9 isoenzymes (e.g. fluconazole). May increase serum level of lithium. May reduce effect of antihypertensives and diu...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.