Medicine Overview of Defrol Syrup 1000IU/5ml Oral Solution
বাংলা
English
Indication
Osteoporosis, Hypoparathyroidism, Rickets, Osteomalacia,Vitamin D Deficiency, Pseudohypoparathyroidism, Familial hypophosphatemia
Administration
May be taken with or without food.
Adult Dose
Oral /IM:
Nutritional deficiency
Colecalciferol (Vitamin D3) is recommended 5-10 mcg
or 1-2ml (200-400 IU)/day
Osteoporosis
Prophylaxis and treatment
>50 years: 800-1000 IU (20-25 mcg) PO once daily with calcium supplements. May also be giv...
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Child Dose
Nutritional Supplementation
RDA
0-12 months: 400 IU (10 mcg) PO once daily
1-18 years: 600 IU (15 mcg) PO once daily
Vitamin D-Resistant Rickets
12,000-500,000 IU (0.3-12.5 mg) PO once daily
Familial Hypophosphatemia
40,000-80,000 IU (1-2 ...
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Contraindication
Colecalciferol is contraindicated in all diseases associated with hypercalcaemia. It is also contraindicated in patients with known hypersensitivity to Colecalciferol (or medicines of the same class) and any of the constituent excipients. Colecalcife...
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Mode of Action
Vitamin D3 is a fat-soluble sterol. It is necessary for the regulation and regulation of calcium and phosphate homoeostasis and bone mineralisation. Vitamin D is also essential for healthy bones as it aids in Calcium absorption from the GI tract. In ...
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Precaution
People with the following conditions should exercise caution when considering taking vitamin D supplements:
High blood Calcium or Phosphorus level
Heart problems
Kidney disease
Vitamin D must be taken with adequate amounts of both Calcium and M...
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Side Effect
Generally all nutritional supplements are considered to be safe and well tolerable. However, few side-effects can generally occur including hypercalcaemia syndrome or Calcium intoxication (depending on the severity and duration of hypercalcaemia), oc...
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Interaction
Increased risk of hypercalcaemia if given with thiazide diuretics, calcium or phosphate. Antiepileptics (e.g. carbamazepine, phenobarbitone, phenytoin & primidone) may increase vitamin D requirements. Rifampicin & isoniazid may reduce efficacy of vit...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.