Briva may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Ple...
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CONSULT YOUR DOCTOR
Information regarding the use of Briva during breastfeeding is not available. Please consult your doctor.
UNSAFE
Briva may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Briva is safe to use in patients with kidney disease. No dose adjustment of Briva is recommended.
It is not recommended in end-stage renal disease due to a lack of clinical trial data.
CAUTION
Briva should be used with caution in patients with liver disease. Dose adjustment of Briva may be needed. Please consult your doctor.
Medicine Overview of Briva 10mg/ml Oral Solution
Introduction
Briva is an anti-epileptic medicine used to treat seizures (fits) in epilepsy. It can be used alone or along with other medicines. It helps to prevent seizures for as long as you continue to take it.
Briva suppresses the abnormal electrical activity...
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Uses of Briva
Epilepsy/Seizures
Side effects of Briva
Common
Dizziness
Fatigue
Nausea
Sleepiness
Vomiting
Constipation
Irritation
How to use Briva
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Briva may be taken with or without food, but it is better to take it at a fixed time.
How Briva works
Briva is an antiepileptic medication. It works by attaching itself to specific sites (SV2A) on the surfaces of nerve cells. This suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause...
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Quick Tips
Briva should be taken regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Inform your doctor if you have a history of liver disease, kidney disease or drug abuse.
Do not stop using Briva without talking to your doctor, even if you feel better.
Brief Description
Indication
Partial-Onset Seizures, Adjunctive therapy in treating partial-onset seizures w/ or w/o secondary generalisation in adults & adolescents ≥16 yr w/ epi...
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Adult Dose
Partial-Onset Seizures
Indicated for partial-onset seizures
50 mg PO/IV q12hr initially; based on individual patient tolerability and therapeutic ...
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Child Dose
Partial Onset Seizures
Tablets or oral solution
Indicated for partial-onset seizures in children and adolescents ?4 years
<4 years: Safety and ef...
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Renal Dose
Renal impairment
Mild-to-moderate: No dose adjustment required
ESRD undergoing dialysis: Not studied
Contraindication
Hypersensitivity; bronchospasms and angioedema have occurred
Mode of Action
Exact mechanism unknown
Displays a high and selective affinity for synaptic vesicle protein 2A (SV2A) in the brain, which may contribute to the ant...
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Precaution
Monitor patients for signs of suicidal ideation & behaviours. Minor or moderate influence on the ability to drive & use machines. Hepatic impairment. ...
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Side Effect
>10%
Somnolence and sedation (16%)
Dizziness (12%)
1-10%
Fatigue (9%)
Nausea and vomiting (5%)
Cerebellar coordination and balance distu...
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Pregnancy Category Note
Pregnancy
No adequate and well-controlled studies in pregnant women
In animal studies, brivaracetam produced evidence of developmental toxicity at...
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Interaction
Doubled effect of alcohol on psychomotor function, attention & memory. Possible increase in plasma conc w/ strong CYP2C19 inhibitors (eg, fluconazole,...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.