It is not known whether it is safe to consume alcohol with Sofosvel. Please consult your doctor.
SAFE IF PRESCRIBED
Sofosvel is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Sofosvel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Sofosvel may cause side effects which could affect your ability to drive.
Sofosvel, when taken together with other medicines for the treatment of hepatitis c infection, may produce dizziness, blurred vision and this may affect your ability to drive.
CAUTION
Sofosvel should be used with caution in patients with severe kidney disease. Dose adjustment of Sofosvel may be needed. Please consult your doctor.
Limited information is available on the use of Sofosvel in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
SAFE IF PRESCRIBED
Sofosvel is safe to use in patients with liver disease. No dose adjustment of Sofosvel is recommended.
However, inform your doctor if you have any kidney disease as regular monitoring of liver function tests may be advised in some patients while taking this medicine.
Medicine Overview of Sofosvel 400mg+100mg Tablet
Introduction
Sofosvel is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection.
Sofosvel should be taken in the prescribe ... Show more
Uses of Sofosvel
Chronic hepatitis C virus (HCV) infection
Side effects of Sofosvel
Common
Headache
Tiredness
How to use Sofosvel
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sofosvel may be taken with or without food, but it is better to take it at a fixed time.
How Sofosvel works
Sofosvel is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.
Quick Tips
Sofosvel is used for the treatment of chronic hepatitis C virus (HCV) infection.
Take it with food, preferably at the same time everyday.
You will usually need to take this medicine every day for either 12 or 24 weeks.
Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.
Sofosvel may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.
Do not stop taking this medicine without your doctor’s advice.
Brief Description
Indication
Chronic Hepatitis C
Administration
May be taken with or without food
Adult Dose
Oral
Adult
Chronic Hepatitis C
Indicated for adults with chronic hepatitis C virus (HCV) infection genotypes 1, 2, 3, 4, 5, and 6
1 tablet (400 mg ... Show more
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment
Severe renal impairment (eGFR <30mL/min/1.73 m²) or ESRD: No dosage recommendation can be give owing to higher exposures (up to 20-f ... Show more
Contraindication
Hypersensitivity.
Mode of Action
Sofosbuvir: Inhibitor of HCV NS5B RNA-dependent polymerase; its inhibition, in turn, suppresses viral replication
Velpatasvir: Pangenotypic HCV NS5A ... Show more
Precaution
Direct-acting antivirals (DDAs) may reactivate hepatitis B virus (HBV) in patients who have a current or previous HBV infection while being treated fo ... Show more
Side Effect
>10%
Without cirrhosis or with compensated cirrhosis
Headache (22%),Fatigue (15%)
With decompensated cirrhosis
Fatigue (32%),Anemia (26%),Hemogl ... Show more
Interaction
Coadministration with drugs that increase gastric pH are expected to decrease velpatasvir serum concentration
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.