Fonidel is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Fonidel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CONSULT YOUR DOCTOR
It is not known whether Fonidel alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Fonidel should be used with caution in patients with kidney disease. Dose adjustment of Fonidel may be needed. Please consult your doctor.
Use of Fonidel is not recommended in patients with severe kidney disease.
CAUTION
Fonidel should be used with caution in patients with severe liver disease. Dose adjustment of Fonidel may be needed. Please consult your doctor.
Medicine Overview of Fonidel 2.5mg/0.5ml Injection
Introduction
Fonidel is an anticoagulant medicine used in the treatment of deep vein thrombosis (clot in veins of leg) and pulmonary embolism (clot in artery of lungs). It helps to prevent formation of harmful blood clots in blood vessels.
Fonidel also reduces t ... Show more
Uses of Fonidel
Deep vein thrombosis
Pulmonary embolism
Side effects of Fonidel
Common
Bleeding
Anemia (low number of red blood cells)
How to use Fonidel
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Fonidel works
Fonidel is an anticoagulant. It stops the action of a substance (clotting factor Xa) from working in the blood. This prevents the formation of unwanted blood clots (thrombosis) in the blood vessels.
What if you forget to take Fonidel?
If you miss a dose of Fonidel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Fonidel prevents the formation of blood clots in the blood vessels of legs or lungs.
It may make you feel dizzy, tired or weak. Do not drive or do anything that requires mental focus until you know how it affects you.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Administration
Administer initial dose 6-8 hours after surgery, once hemostasis has been established
SC administration is deep, alternating right ... Show more
Adult Dose
Deep Vein Thrombosis/Acute Pulmonary Embolism
Treatment
<50 kg: 5 mg SC once daily
50-100 kg: 7.5 mg SC once daily
>100 kg: 10 mg SC once daily
A ... Show more
Hypersensitivity. Active clinically significant bleeding, acute bacterial endocarditis.
Mode of Action
Fondaparinux, a synthetic pentasaccharide, acts as a selective inhibitor of activated factor X. It works by binding selectively to ATIII, and potentia ... Show more
Precaution
Patient w/ increased risk of haemorrhage (e.g. congenital or acquired bleeding disorders, history or active GI ulceration, intracranial haemorrhage, r ... Show more
Side Effect
>10%
Anemia (1-20%),Fever (4-14%),Nausea (3-11%)
1-10%
Rash (7.5%),Dizziness (4%),Confusion (3%),Constipation (5-9%),Diarrhea (2-3%),Edema (9%),H ... Show more
Pregnancy Category Note
Pregnancy
Available data from published literature and postmarketing reports have not reported clear association with adverse developmental outcomes; ... Show more
Interaction
Increased risk of bleeding w/ (e.g. desirudin, fibrinolytic drugs, glycoprotein IIb/IIIa-receptor antagonists, heparin, heparinoids or LMWH).
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.