It is not known whether it is safe to consume alcohol with Xpos 100 DR. Please consult your doctor.
CONSULT YOUR DOCTOR
Xpos 100 DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Xpos 100 DR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Xpos 100 DR may cause side effects which could affect your ability to drive.
As you may feel dizzy, sleepy, or have blurred vision while taking Xpos 100 DR, which may affect your ability to drive.
CAUTION
Xpos 100 DR should be used with caution in patients with kidney disease. Dose adjustment of Xpos 100 DR may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advised while taking this medicine. Use of Xpos 100 DR is not recommended in patients with moderate to severe kidney disease.
SAFE IF PRESCRIBED
Xpos 100 DR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Xpos 100 DR may not be needed in these patients. Please consult your doctor.
Medicine Overview of Xpos 100 DR 100mg Tablet
Introduction
Xpos 100 DR belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat fungal infection. It kills fungi by destroying the fungal cell membrane.
Xpos 100 DR is an injectable drug and given as an ... Show more
Uses of Xpos 100 DR
Severe fungal infections
Side effects of Xpos 100 DR
Common
Headache
Vomiting
Cough
Nausea
How to use Xpos 100 DR
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Xpos 100 DR works
Xpos 100 DR is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your infection.
Quick Tips
Your doctor has prescribed Xpos 100 DR to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
It is given as an injection under the supervision of a healthcare professional.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of ... Show more
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Brief Description
Indication
Prophylaxis of invasive Aspergillus, Candida Infections, Oropharyngeal candidiasis
Administration
IV Preparation
Equilibrate the refrigerated vial to room temperature
Aseptically transfer 16.7 mL (300 mg) of solution to an IV bag/bottle containin ... Show more
Adult Dose
Oral
Prophylaxis of invasive fungal infections
Adult: As delayed-release tab: 300 mg bid on the 1st day, then 300 mg once daily thereafter. As oral ... Show more
Child Dose
Invasive Aspergillus & Candida Infections
Indicated for prophylaxis of invasive Aspergillus and Candida infections in patients who are at high risk o ... Show more
Renal Dose
Moderate-to-severe renal impairment (IV)
eGFR <50 mL/min: Avoid IV administration unless benefit/risk assessment justifies use
Accumulation of the I ... Show more
Contraindication
Hypersensitivity. Co-admin w/ sirolimus, ergot alkaloids (e.g. ergotamine, dihydroergotamine), CYP3A4 substrates (terfenadine, astemizole, cisapride, ... Show more
Mode of Action
Blocks the synthesis of ergosterol, a key component of the fungal cell membrane, through the inhibition of the enzyme lanosterol 14-α-demethylase and ... Show more
Precaution
Patient w/ potentially proarrhythmic conditions. Hepatic impairment. Pregnancy and lactation. Patient Counselling May impair ability to drive or opera ... Show more
Side Effect
>10%
Fever (45%)
Diarrhea (42%)
Nausea (38%)
Hypokalemia (30%)
Headache (28%)
Abd pain (27%)
Anemia (25%)
Cough (24%)
Nausea ... Show more
Pregnancy Category Note
Pregnancy
Available data in pregnant women are insufficient to establish a drug- associated risk of major birth defects, miscarriage, or adverse mate ... Show more
Interaction
Decreased plasma concentrations w/ efavirenz, fosamprenavir, cimetidine, esomeprazole, metoclopramide, phenytoin and rifabutin. May increase plasma co ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.