Caution is advised when consuming alcohol with Apixan 5. Please consult your doctor.
SAFE IF PRESCRIBED
Apixan 5 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CONSULT YOUR DOCTOR
Apixan 5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
SAFE
Apixan 5 does not usually affect your ability to drive.
CAUTION
Apixan 5 should be used with caution in patients with kidney disease. Dose adjustment of Apixan 5 may be needed. Please consult your doctor.
CAUTION
Apixan 5 should be used with caution in patients with liver disease. Dose adjustment of Apixan 5 may be needed. Please consult your doctor.
Dose adjustment is not needed in patients with the mild liver disease.
Medicine Overview of Apixan 5mg Tablet
Introduction
Apixan 5 is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and hea ... Show more
Uses of Apixan 5
Deep vein thrombosis
Pulmonary embolism
Stroke prevention
How to use Apixan 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apixan 5 may be taken with or without food, but it is better to take it at a fixed time.
How Apixan 5 works
Apixan 5 is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.
What if you forget to take Apixan 5?
If you miss a dose of Apixan 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
For best results, take Apixan 5 at the same time every day. It is better to take at night with meals
It interacts less with food or other medicines. Hence, frequent dose changes are not required.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sp ... Show more
Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
If you are going to have a surgery or dental treatment, you may be asked to stop taking Apixan 5 temporarily.
Notify your doctor if you have any kidney problem.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking medication without talking to your doctor.
Brief Description
Indication
Indicated to reduce risk of stroke and systemic embolism associated with nonvalvular atrial fibrillation, Postoperative Prophylaxis of DVT/PE followin ... Show more
Administration
May be taken with or without food.
Adult Dose
Oral
Adult
Prevention of VTE: Elective hip or knee replacement surgery
Tablet 2.5 mg twice daily. Initial dose should be taken 12-24 hr post-op.
... Show more
Renal Dose
Renal impairment, including with ESRD on dialysis
Deep Vein Thrombosis: No dose adjustment recommended; clinical efficacy and safety studies did not ... Show more
Contraindication
Hypersensitivity. Clinically significant active bleeding. Hepatic disease associated w/ coagulopathy & clinically relevant bleeding risk. Lesion or co ... Show more
Mode of Action
Apixaban is an anticoagulant that inhibits platelet activation and fibrin clot formation via direct, selective and reversible inhibition of free and c ... Show more
Precaution
Increased risk of hemorrhage eg, congenital or acquired bleeding disorders; active ulcerative GI disease; bacterial endocarditis; thrombocytopenia; pl ... Show more
Side Effect
Epistaxis, haematoma, anaemia, haematuria, contusion, nausea; GI, rectal or gingival haemorrhage.
Potentially Fatal: Epidural or spinal haematoma, fa ... Show more
Pregnancy Category Note
Pregnancy
There are no adequate and well-controlled studies in pregnant women
Treatment is likely to increase the risk of hemorrhage during pregna ... Show more
Interaction
Increased exposure w/ strong dual CYP3A4 and P-glycoprotein (P-gp) inhibitors (e.g. clarithromycin, itraconazole, ketoconazole, ritonavir). Increased ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.